摘要
目的应用QCT测量武进区城乡中老年人腰椎骨密度,掌握骨质疏松、脊柱骨折发病情况,分析骨质疏松症与脊柱脆性骨折的相关性。方法对武进区600例城乡志愿者行上腹部低剂量QCT扫描,测量腰椎骨密度,记录脊柱骨折发生情况,依据骨质疏松诊断标准分为骨密度正常、低骨量、骨质疏松、严重骨质疏松四组,采用方差分析、卡方检验比较四组间骨密度测量值、脊柱骨折发生情况有无明显统计学差异。绘制脊柱脆性骨折发生部位统计图。结果骨质疏松检出率为24.83%(149/600),严重骨质疏松组脊柱脆性骨折检出率(54.5%)最高,其次为骨质疏松组(15.5%),四组间骨密度测量值无统计学意义(P=0.1328),而脊柱脆性骨折发病情况有显著统计学意义(P=0.000<0.01)。脊柱脆性骨折主要位于L_1、T_(12)、L_2,检出率分别为31.14%、29.5%和11.48%。结论 QCT测量腰椎BMD为OP早期发现、早期治疗和预防脊柱脆性骨折及预测骨折再发生提供了可靠的临床依据。脊柱脆性骨折的发病率与OP严重程度存在一定正相关。
Objective To measure lumbar BMD of the middle and old age in wujin district by using QCT,to master the incidence of osteoporosis,vertebral fracture,and to analyze the correlation between osteoporosis and vertebral fracture. Methods The 600 urban and rural volunteers in wujin district underwent abdominal low dose QCT scanning. We measured lumbar bone density and recorded spinal fracture occurrence. According to the diagnostic criteria of osteoporosis,those were divided into normal bone density,low bone mass,osteoporosis and severe osteoporosis in four groups. Variance analysis and Chi square test were used to compare the differences between the four groups in the measurement of bone mineral density and the incidence of spinal fracture. The circular statistical chart of the location of spinal fracture was drawn. Results Incidence of osteoporosis was 24. 83%（ 149/600）,brittle fracture incidence of severe osteoporosis group was highest（ 54. 5%）,followed by osteoporosis group（ 15. 5%）,BMD between the four groups was not statistically significant（ P = 0. 1328）,the brittle fracture incidence had statistical significance（ P = 0. 000 0. 01）. Incidence of brittle fracture in L1,T12,L2 was 31. 14%,29. 5% and 11. 48% respectively. Conclusion Lumbar BMD measurement by applying QCT provides a reliable clinical basis for early detection and early treatment of OP,and prevention of spinal fracture and prediction of spinal fracture recurrence. The incidence of brittle fracture of the spine and the severity of OP is positively correlated.
出处
《医学影像学杂志》
2017年第12期2368-2370,共3页
Journal of Medical Imaging
关键词
骨密度
体层摄影术
X线计算机
骨质疏松
脊柱
脆性骨折
Bone mineral density
Tomography, X-ray computed
Osteoporosis
Spine
Brittle fracture
