摘要
目的比较前列安栓联合α受体阻滞剂与单用前列安栓两种方法对Ⅲ型前列腺炎的治疗效果。方法 2016年10月,系统检索Pub Med、Cochrane图书馆、Embase、万方数据库、维普数据库、CNKI数据库,筛选出关于前列安栓联合α受体阻滞剂与单用前列安栓两种方法治疗Ⅲ型前列腺炎的所有对比性研究,并通过Rev Man 5.2软件进行Meta分析。结果总共6篇文献纳入研究,Meta分析显示:与单用前列安栓相比,前列安栓联合α受体阻滞剂能显著提高Ⅲ型前列腺炎患者的治愈率(RR=1.58,95%CI:1.29~1.94,P<0.000 01)、总有效率(RR=1.29,95%CI:1.20~1.39,P<0.00001)及慢性前列腺炎症状评分(CPSI评分)(MD=-4.81,95%CI:-5.07^-4.55,P<0.000 01)。结论前列安栓联合α受体阻滞剂较单纯使用前列安栓治疗Ⅲ型前列腺炎效果更佳,可推荐其作为临床上治疗Ⅲ型前列腺炎的有效选择。
Objective To compare the efficiency of Prostant combined with α-blockers and single Prostant for type Ⅲ prostatitis. Methods We systematically searched all comparative studies focusing on these two therapies for type Ⅲ prostatitis based on the databases of Pub Med, Cochrane Library, Embase, Wanfang, VIP and CNKI. A meta-analysis was then carried out taking advantage of Rev Man 5.2 software. Results Meta-analysis of all six articles showed that, compared with single Prostant for type Ⅲ prostatitis, combination medication could significantly improve the cure rate（RR=1.58, 95% CI： 1.29-1.94, P〈0.000 01）, overall effective rate（RR=1.29, 95% CI： 1.20-1.39, P〈0.000 01） and chronic prostatitis symptom index（CPSI）（MD =-4.81, 95% CI：-5.07--4.55, P〈0.000 01）. Conclusion Combination of Prostant and α-blockers could be more effective for type Ⅲ prostatitis compared to single Prostant, and it could be recommended as a clinically favorable choice.
出处
《海南医学》
CAS
2017年第22期3755-3758,共4页
Hainan Medical Journal
