摘要
目的:观察中西医结合治疗十二指肠溃疡的临床疗效。方法:选取本院2013年1月—2014年12月门诊或住院患者74例,按照随机数字表法分为对照组和治疗组,每组37例。对照组予托拉唑钠肠溶片、枸橼酸铋钾、阿莫西林治疗,治疗组在对照组治疗的基础上加用中药补气愈溃汤治疗,两组均以15 d为1个疗程,治疗1个疗程后比较两组疗效。结果:对照组有效率为83.78%,治疗组有效率为94.59,两组有效率比较差异有统计学意义(P<0.05);治疗组治疗后溃疡面积积分和溃疡疼痛积分优于对照组(P<0.05);治疗组治疗后IL-8、TNF-α、MPO、SOD和MDA水平优于对照组(P<0.05),治疗组治疗后IL-6水平与对照组比较,差异无统计学意义(P>0.05);治疗组主观支持分、客观支持分、支持利用度及总分优于对照组(P<0.05)。结论:中西医结合治疗十二指肠溃疡疗效肯定,能显著减轻患者疼痛,无不良反应。
Objective：To observe the clincial effects of integrative Chinese and western medicine on duodenal ulcer （DU）. Meth- ods ：Totally 74 patients with DU treated between January 2013 and December 2014 were randomized into control group and treat- ment group,37 cases in each group. Control group were given Pantoprazole Sodium Enteric-Coated Tablets, Bismuth Potassium Cit- rate and Amoxicillin while treatment group were additionally given Qi-Tonifying and Ulcer-Curing Decoction for the treatment, 15 d as a treatment course for both groups. The therapeutic effec, ts in the two groups were compared after 1 treatment course. Results ： The effective rate was 83.78% in control group and 94.59% in treatment group;the difference had statistical significance （P 〈 0.05 ）. The levels of IL-8,TNF-a, MPO, SOD and MDA in treatment group were superior to those in control group （ P 〈 0.05 ）. The difference of the levels of IL-6 between two groups had no statistical significance （P 〉 0.05 ）. The subjective support score, objective support score, support utilization degree and total score in treatment group were superior to those in control group （ P 〈 0. 05）. Conclusion ：Integrative Chinese and western medicine has definite therapeutic effects on DU, which can significantly re- duce pain of the patients without adverse reactions.
出处
《河南中医》
2017年第12期2159-2161,共3页
Henan Traditional Chinese Medicine
基金
2016河南省中医管理局重大立项项目(编号:2016ZY2047)
关键词
补气愈溃汤
十二指肠溃疡
托拉唑钠肠溶片
枸橼酸铋钾
阿莫西林
中西医结合疗法
Qi-Tonifying and Ulcer-Curing Decoction
duodenal ulcer （ DU ）
Pantoprazole Sodium Enteric-Coated Tablets
Bis- muth Potassium Citrate
Amoxicillin
therapy of integrative Chinese and western medicine
