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真菌血流感染病原菌分布及对抗真菌药的敏感性分析 被引量:8

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摘要 目的分析我院2014年06月~2017年06月真菌血流感染病原学分布及对抗真菌药的敏感性,为临床用药提供参考依据。方法临床送检的血培养经Bact/Alert 3D血培养仪培养,经科玛嘉显色平板、YST鉴定卡或API 20C AUX试剂条进行鉴定,用药敏试剂条ATB Fungus3或氟康唑药敏纸片法进行药敏试验,并对真菌菌种分布及药敏结果做统计学分析。结果经血培养分离到的真菌共89株,多分布于高龄老年患者和重症监护室,以白色念珠菌(29,32.58%)、近平滑念珠菌(15,16.85%)、热带念珠菌(14,15.73%)和光滑念珠菌(9,10.11%)为多见,MIC法药敏结果显示对氟康唑敏感性分别为:100%、92.85%、100%、75.00%。76株采用MIC法显示对抗真菌药总敏感性依次为:两性霉素B为100%,5-氟胞嘧啶为97.37%,氟康唑和伏立康唑均为90.78%,伊曲康唑为77.63%。结论真菌血流感染以白色念珠菌为主,绝大多数真菌对抗真菌药具有较高敏感性,尚未出现对两性霉素B耐药菌株。
出处 《海峡药学》 2017年第12期140-142,共3页 Strait Pharmaceutical Journal
基金 福建省引导类项目(2016Y0015)
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