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面神经炎治疗前后神经电生理变化的临床研究 被引量:6

Clinical study of neuroelectrophysiological changes before and after treatment of facial neuritis
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摘要 目的观察面神经炎治疗前后神经电生理变化。方法以2013-01—2016-12在聊城市人民医院脑科医院接受治疗的84例面神经炎患者为研究对象,分别于治疗前后检测患者面神经电图和瞬目反射,并进行患侧与健侧比较。结果治疗后较治疗前House-Brackmann分级明显改善(P<0.05),面肌功能评分明显升高(P<0.05)。治疗前,患侧较健侧R1、R2、R2’波潜伏期均明显延长(P<0.05);治疗前,患侧较健侧面神经电图潜伏期及瞬目反射R1、R2、R2’波潜伏期均明显延长(P<0.05),面神经波幅明显降低(P<0.05);治疗后,患侧面神经电图潜伏期及R1、R2、R2’波潜伏期较治疗前均明显缩短(P<0.05),面神经波幅明显增大(P<0.05),且与健侧比较无显著差异(P>0.05)。结论神经电生理检测或许有助于面神经炎诊断,病情严重程度评估,并对预后判断有指导作用。 Objective To observe the neuroelectrophysiological changes before and after treatment of facial neuritis . Methods 84 cases of patients with facial neuritis treated in our hospital from January 2013 to December 2016 were included in the study .The electroneurography and blink reflex were detected before and after treatment ,and the affected side and contralateral side were compared .Results The House-Brackmann grade after treatment was significantly improved compared with that before oper-ation (P〈0.05) ,and the facial muscle function score was significantly increased (P〈0.05) .Before treatment ,the latencies of R1 ,R2 and R2'waves in the affected side were significantly prolonged compared with those in the contralateral side (P〈0.05) . Before treatment ,the latency of electroneurography and the latencies of blink reflex R1 ,R2 and R2'waves in the affected side were significantly prolonged compared with those in the contralateral side (P〈0.05) ,and the amplitude of facial nerve was significantly decreased (P〈0.05) .After treatment ,the latency of electroneurography and the latencies of R1 ,R2 and R2'waves in the affected side were significantly shortened compared with those before treatment (P〈0.05) ,and the amplitude of facial nerve was signifi-cantly increased (P〈0.05) ,and there was no significant difference compared with those in the contralateral side (P〉0.05) .Con-clusion Neuroelectrophysiological test may be helpful for the diagnosis of facial neuritis and the assessment of disease severity , and can have guiding role in prognostic judgment .
出处 《中国实用神经疾病杂志》 2017年第24期51-54,共4页 Chinese Journal of Practical Nervous Diseases
基金 山东省自然科学基金高校 科研单位联合专项项目 编号:ZR2013HL017
关键词 面神经炎 神经电生理 神经节苷脂 周围性面瘫 面神经水肿 Facial neuritis Neuroelectrophysiology Gangliosides Peripheral falial pararysis Facial nervedema
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