摘要
目的探讨急性脑梗死患者血浆纤维蛋白原(FIB)和D-二聚体(D-D)水平的变化及临床意义。方法检测和比较85例急性脑梗死患者和对照组50例健康人群血浆FIB和D-D水平。结果脑梗塞组患者血浆FIB和D-D水平均高于对照组,两组比较差异有统计学意义(P<0.01)。不同临床分型急性脑梗死患者间血浆FIB和D-D水平,比较具有统计学差异,大面积梗死组>中等面积梗死组>腔隙性梗死组(P<0.01)。结论联合检测FIB水平和D-D在预测脑梗死面积和判断病情严重程度方面具有重要的临床意义。
Objective To investigate the changes and clinical significance of plasma fibrinogen （FIB） and D-dimer （D-D） in patients with acute cerebral infarction. Methods The plasma levels of FIB and D-D were measured and compared in 85 patients with acute cerebral infarction and 50 healthy controls. Results The average plasma FIB and D-D levels in the patients with cerebral infarction were higher than those of the control group, and the difference between the two groups was statistically signifcant （P〈0.01）. There were signifcant differences in plasma FIB and D-D levels between different clinical types of acute cerebral infarction, large area infarction group 〉 middle area infarction group 〉 lacunar infarction group （P〈0.01）. Conclusion Detecting the levels of plasma FIB and D-D has an important clinical signifcance in predicting the area and the severity of cerebral infarction.
出处
《临床检验杂志（电子版）》
2017年第4期635-637,共3页
Clinical Laboratory Journal(Electronic Edition)
