摘要
目的研究大剂量甲强龙冲击加小剂量免疫抑制剂治疗甲亢突眼的效果及不良反应。方法选取甲亢突眼患者56例,随机分为观察组及对照组,各28例,对照组采用静脉注射甲强龙,观察组给予大剂量甲泼尼龙琥珀酸钠(甲强龙)加小剂量免疫抑制剂治疗,观察两组患者疗效。结果观察组患者总有效率为96.43%,对照组总有效率为64.29%,观察组患者总有效率高于对照组(P<0.05);两组患者不良反应差异无统计学意义(P>0.05)。结论甲强龙联合免疫抑制剂治疗甲亢突眼效果显著。
Objective To study the effcacy and adverse reactions of large dose methylprednisolone plus small dose of immunosuppressive agents in the treatment of graves ophthalmopathy. Methods 56 patients with graves ophthalmopathy patients were randomly divided into observation group and control group, each of 28 cases, control group with intravenous methylprednisolone, observation group were given large doses of methylprednisolone plus low dose of immunosuppressant, the effcacy of the two groups was observed. Results The total effective rate of the observation group was 96.43%, and the total effective rate of the control group was 64.29%. The total effective rate of the observation group was higher than that of the control group （P 〈 0.05）. The difference of the adverse reactions between the two groups was not statistically signifcant （P 〉 0.05）. Conclusion Methylprednisolone combined with immunosuppressive in the treatment of hyperthyroidism exophthalmos has signifcant effect.
出处
《中国卫生标准管理》
2018年第1期72-73,共2页
China Health Standard Management
关键词
甲强龙
免疫抑制剂
甲亢突眼
methylprednisolone
immunosuppressant
hyperthyroidism exophthalmos
