摘要
目的:通过分析3种中药注射液文献报道的个案不良事件(adverse drug events,ADE)的规律及特点,探究其发生的影响因素,为临床合理用药提供有价值的参考。方法:本文采用文献计量学方法,对CNKI数据库收录近15年的文献进行分类统计分析。结果:喜炎平(65.00%)和热毒宁(75.86%)14岁以下患者构成比较高;原患疾病主要为呼吸系统疾病;损伤系统主要为皮肤及其附件,其次为全身;不良事件大部分发生在用药开始后30min内;联合用药以抗微生物药物为主。结论:不良事件的发生和药物本身因素、患者自身情况等相关,建议临床医生合理用药,降低药物使用风险。
bObjective： Through research on the rules and characteristics of ADE, the effect and influence factors of three kinds of Chinese medicine injections were explored to provide references for the clinical use. Methods： By bibliometric analysis, statistical analysis for the recent 15 years＇ literatures was performed in CNKI databases. Results： The most common disease of cases of ADE was the respiratory diseases; the constituent ratio of cases under age 14 of Xiyanping（65%）and Reduning（75.86%）had a higher rate; the most common type of ADEs was skin and its accessories damage, followed by the whole body reaction. Most of cases occurred in 30 min after the transfusion begins; the drug combination was included chiefly antimicrobial drugs. Conclusion： The cases of ADEs were mainly caused by drug factor, body constitution and so on. Clinicians should pay attention to rational drug use, so as to reduce the risk.
出处
《药品评价》
CAS
2017年第23期20-22,29,共4页
Drug Evaluation
关键词
痰热清
喜炎平
热毒宁
不良事件
文献分析
Tanreqing
Xiyanping
Reduning
Adverse Drug Events
Bibliometric Analysis
