摘要
目的对比经尿道前列腺钬激光剜除术（holmium laser enueleation of prostate，HoLEP）与前列腺电切术（transurethral resection of theprostate，TURP）的短期临床疗效。方法随机选取良性前列腺增生症（BPH）患者88例，HoLEP治疗患者44例，TuRP治疗患者44例。比较2组手术中相关指标及术后6个月随访进行国际前列腺症状评分（wss）、生活质量评分（QOL）、残余尿量（（PVR）测定。结果HoLEP组患者手术时间比TuRP组长，术中失血量、导尿管留置时间以及住院时间HoLEP组均显著低于对照组，差异均具统计学意义（P〈0．05）。术后6个月随访，HoLEP组IPSS、QOL评分与TURP组相比无显著差异，残余尿量HoLEP组显著低于TuRP组，差异具有统计学意义（P〈0．05）。结论2种治疗方式近期疗效相当，但HoLEP可明显降低出血量、减少导尿管留置时间、缩短住院时间、降低术后残余尿量，值得推广。
Objective To compare the short - term efficacy of the holmium laser enucleation of the prostate （ Ho- LEP） with the transurethral resection of prostate （TURP） in the treatment of benign prostatic hyperplasia （BPH）. Methods A total of 88 patients with BPH were randomized to either treated with HoLEP （ n = 44） or TURP （ n = 44）. Perioperative parameters were recorded and analyzed. Postoperative evaluations including the：international prostate symp- tom score （IPSS）, the quality of life score （QOL） , residual urine volume （PVR） were conducted at 6 months. Results Patients in the HoLEP group had significantly longer operating time and shorter catheterization times and hospital stays and less blood loss than those in the TURP group （ P 〈 O. 05 ）. At the 6 months follow - up no significant differences were observed in the IPSS and QOL between two groups and there was a significantly greater improvement in PVR urine vol- umes in the HoLEP group （ P 〈 0.05 ）. Conclusion Compared to TURP, HoLEP is proved to lead equally effeetive and less invasion. Although there are many difficulties to learn this technology, it should to be extended in the clinical application.
出处
《徐州医科大学学报》
CAS
2017年第12期829-831,共3页
Journal of Xuzhou Medical University
