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10例SAPHO综合征临床分析 被引量:2

Clinical analysis of 10 patients with SAPHO syndrome
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摘要 10例患者中(男女各5例)发病年龄21~63岁。10例患者均有掌跖脓疱病、痤疮、银屑病样皮损。影像学检查示前胸壁受累10例;脊柱受累6例;外周骨关节受累3例;髋关节受累2例;并发结节性甲状腺肿1例。10例均给予免疫调节药物,8例给予非甾体抗炎药,2例给予手术治疗。6例患者关节及皮肤症状均好转,2例仅有皮肤好转,1例仅有骨关节症状好转,1例反复发作。 The range of age in ten patients( 5 males and 5 females) at onset was from 21 to 63 years old.The all 10 patients presented as palmoplantar pustulosis,acne and psoriasis-like lesions. Imageological examination showed that the anterior chest wall was involved in 10 patients,spinal involvement in 6,peripheral bone and joint in 3,hip joint in 2. One patient was complicated with nodular goiter. Ten patients were given immunization medication,8 cases were given non-steroidal anti-inflammatory drugs( NSAIDs) and 2 patients were given surgical treatment. The symptoms of arthritis and skin lesions were improved in 6 patients,only skin lesions were improved in 2,only arthritis was improved in one and the treatment was ineffective in one.
出处 《中国麻风皮肤病杂志》 2017年第12期712-716,共5页 China Journal of Leprosy and Skin Diseases
基金 国家自然科学基金(编号:81673054)
关键词 SAPHO综合征 掌跖脓疱病 痤疮 骨关节炎 非甾体抗炎药 SAPHO syndrome palmoplantar pustulosis acne osteoarthritis nonsteroidal anti-inflammatory drugs
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