期刊文献+

电解质分析仪检定过程中的基质效应变化规律研究 被引量:2

Research on the Variation of Matrix Effect in the Verification of Electrolyte Analyzer
下载PDF
导出
摘要 为了观察电解质分析仪计量检定过程中基质效应的变化规律,使用水溶液基质的定标液对电解质分析仪进行校准和使用人血清基质的定标液对生化分析仪进行校准后,再对不同浓度的水溶液基质标准物质和人血清基质标准物质分别进行测定,对检定结果进行显著性分析。结果表明,使用人血清基质校准后的生化分析仪和水溶液基质校准后的电解质分析仪的K^+、Na^+、Cl^-检定结果在一定的浓度范围内具有统计学差异(p<0.01),电解质分析仪检定过程中基质效应引起的偏差大小随浓度的变化而变化。 To observe the variation of matrix effect during the metrological verification of the electrolyte analyzer, the electrolyte analyzer using the calibration solution of the aqueous solution matrix, and the biochemical analyzer using the calibration solution of the human serum matrix was calibrated, and then the standard materials of aqueous solution matrixes and human serum matrixes with different concentrations was respectively determined, the significance of the verification results will be analyzed.The test results of K^+, Na^+, and Cl^- are statistically significant (p〈0.01) within certain concentration ranges after the calibration of the biochemical analyzer using human serum matrix and electrolyte analyzer using the aqueous solution matrix.Therefore, the deviation caused by the matrix effect varies with the concentration during the calibration process.
出处 《计量学报》 CSCD 北大核心 2018年第1期130-134,共5页 Acta Metrologica Sinica
基金 国家质量基础的共性技术研究与应用重点专项(2017YFF0204603)
关键词 计量学 电解质分析仪 基质效应 检定 校准 metrology electrolyte analyzer matrix effect verification calibration
  • 相关文献

参考文献5

二级参考文献31

  • 1常碧影,梁冬生,阎惠文,左江湾.氨基酸分析技术研究的进展[J].分析化学,1993,21(10):1220-1227. 被引量:20
  • 2李贵来,石玉梅,杨江存.全血储存期间K^+、Na^+、Cl^-离子浓度的变化[J].西部医学,2005,17(4):397-398. 被引量:10
  • 3蔡耘,武力民,杨松成.MALDI-TOF-MS法分析人血清白蛋白[J].分析测试学报,1996,15(4):80-82. 被引量:4
  • 4The National Conmmittee for Clinical Laboratory Standards. Method Comparison and Bias Estimation Using Patient Samples[S]. Approved Guideline, Second Edition, EP9-A2, 2002.
  • 5Marcovina SM,Adolphson JL,Parlavecchia M,Albers JJ.Effects of lyophilization of serum on the measurement of apolipoprotein A-1 and B[J].Clin Chem,1990;36:366~369.
  • 6Ross JW,Myers GL,Gilinore BF,et al.Matrix effects and the accuracy of cholesterol analysis[J].Arch Pathol Lab Med,1993;117:393~400.
  • 7李健斋,陈文祥.血脂与脂蛋白测定中的基质效应问题(待发表).
  • 8Natio HK,Kwak YS,Hartfiel JL,et al.Matrix effect on proficiency testing materials[J].Arch Pathol Lab Med,1993;117:345~351.
  • 9Eckfedt JH,Coleland JK.Accuracy verification and identification of matrix effects.The college of American Pathologists' Protocol[J].Arch Pathol Lab Med,1993;117:381~386.
  • 10Evaluation of matrix effects. Wayne,PAz Clinical and Laboratory Standards Institute[S]. EP14-A, 2001.

共引文献46

同被引文献18

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部