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长春西汀联合川芎嗪综合治疗急性脑梗死的临床疗效及不良反应分析 被引量:8

Analysis of clinical efficacy and adverse reaction of vinpocetine combined with ligustrazine for comprehensive treatment of acute cerebral infarction
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摘要 目的探讨长春西汀联合川芎嗪综合治疗急性脑梗死的临床疗效及不良反应。方法 50例急性脑梗死患者,根据治疗方法的不同分为对照组(实施长春西汀注射液治疗)和观察组(实施长春西汀注射液联合川芎嗪综合治疗),各25例。观察比较两组患者的临床疗效及不良反应发生情况。结果观察组患者总有效率为92%,显著高于对照组的68%,差异具有统计学意义(P<0.05);观察组患者不良反应发生率明显低于对照组,差异具有统计学意义(P<0.05)。结论给予急性脑梗死患者长春西汀注射液联合川芎嗪综合治疗的临床疗效显著,能够减少不良反应发生,值得临床推广使用。 Objective To discuss the clinical efficacy and adverse reaction of vinpocetine combined with ligustrazine for comprehensive treatment of acute cerebral infarction. Methods A total of 50 acute cerebral infarction patients were divided by different treatment methods into control group (received vinpocetine injection) and observation group (received comprehensive therapy of vinpocetine injection and ligustrazine),, with 25 cases in each group. Observation and comparison were made on clinical efficacy and occurrence of adverse reactions between two groups. Results The observation group had obviously higher total effective rate as 92% than 68% in,the control group, and the difference was statistically significant (P〈0.05). The observation group had obv!ously lower incidence of adverse reactions than the control group, and the difference was statistically significant (P〈0.05). Conclusion Comprehensive therapy of vinpocefine injection and ligustrazine shows remarkable clinical efficacy in treating acute cerebral infarction patients can reduce the occurrence of adverse reactions, and is worthy of clinical promotion and application.
作者 李佳时
出处 《中国实用医药》 2018年第2期69-70,共2页 China Practical Medicine
关键词 长春西汀 川芎嗪 急性脑梗死 临床疗效 不良反应 Vinpocetine Ligustrazine Acute cerebral infarction Clinical efficacy Adverse reaction
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