摘要
目的研究不同中医证型原发性肝癌患者中血小板分布宽度(PDW)、血小板平均体积(MPV)水平的变化及意义。方法采用回顾性研究方法分析2013年1月~2016年12月广西柳州市中医医院收治的155例原发性肝癌患者,根据中医证型将其分为肝气郁结、气滞血瘀、湿热聚毒、肝郁脾虚四组,比较各组PDW、MPV的差异。结果原发性肝癌各中医证型组中肝气郁结组PDW较其余组明显升高(P<0.01),MPV较其余组明显降低(P<0.01)。肝郁脾虚组PDW较气滞血瘀组、湿热聚毒组升高(P<0.01),MPV较其余三组均增高(P<0.01)。结论PDW和MPV可作为原发性肝癌肝气郁结和肝郁脾虚证型的重要参考指标。
Objective To studythe changes and significances of platelet distribution width （PDW）and mean platelet vol ume （MPV） in hepatocellular carcinoma （HCC） patients with different syndrome classified by traditional Chinese Medicine （TCM）. Methods A retrospective study was carried out to analyze the clinical data of 155 HCC patients from January 2013 to December 2016 in Liuzhou Hospital of Traditional Chinese Medicine. All patients was divided into four groups according to TCM syndrome： stagnation of liver-Qi, qi-stagnation and blood stasis, dampness and heat accumulation, stagnation of liver-Qi with deficiency of the spleen.The differences of PDW and MPV among different groups were analyzed. Results The level of PDW in stagnation of liver-Qi group were significantly higher than that of the other groups （P 〈 0.01）, however, the level of MPV in stagnation of liver-Qi group was significantly lower than that of the other groups （P 〈 0.01）. Compared with qi-stagnation and blood stasis and dampness and heat accumulation group, the level of PDW increased significantly in stagnation of liver-Qi with deficiency of the spleen group （P 〈 0.01）, and the level of MPV in the stagnation of liver-Qi with deficiency of the spleen group were significant higher than that of the other three groups （P 〈 0,01）. Conclusion The PDW and MPV can be used as important reference indexes for HCC patients with stagnation of liver-Qi and syndrome of stagnation of liver-Qi with deficiency of the spleen in primary
出处
《中国医药导报》
CAS
2018年第1期102-105,共4页
China Medical Herald
基金
广西中医药大学自然科学研究项目(2014YB14030)
关键词
原发性肝癌
中医证型
血小板分布宽度
血小板平均体积
Primary hepatocellular carcinoma
Syndrome types
Platelet distribution width
Mean platelet volume
