摘要
难治性肾病综合征是指对糖皮质激素抵抗、依赖和(或)频繁复发的肾病综合征,占原发性肾病综合征的30%~50%,其临床表现较重,治疗棘手,预后较差。中医药治疗难治性肾病综合征,在降低尿蛋白及改善临床症状方面疗效突出,且不良反应相对小。但是在辨证客观化、证候规范化、药物作用机制等方面与循证医学要求尚有一定差距,在一定程度上限制了中医的发展。笔者将近年来中医对难治性肾病综合征的辨证、治疗进行总结。
Refractory nephritic syndrome （RNS） is a nephritic syndrome of steroid-resistant, steroid-de- pendent, and （or） frequent recurrent, accounting for 30% to 50% of primary nephrotic syndrome. Its clinical manifestations are serious while the treatment is difficult, and the prognosis is poor. TCM internal treatment used in the treatment of RNS has prominent curative effect in improving clinical symptoms, decreasing proteinuria, and with fewer side effects. However, there is a certain distance to the requirements of objective syndrome differentiation, symptom standardization, mechanism of drug action and so on, which limits the development of TCM to some extent. In this paper, the syndrome differentiation and treatment of refractory nephrotic syndrome in recent years was summarized.
出处
《贵阳中医学院学报》
2018年第1期97-100,共4页
Journal of Guiyang University of Chinese Medicine
基金
贵州省中医药管理局中医药
民族医药科学技术研究课题
项目编号:QZYY2017-043
贵州省科技厅基金项目
项目编号:黔科合基础(2017)1005
关键词
难治性肾病综合征
中医内治法
研究进展
refractory nephritic syndrome
TCM internal treatment
research progress
