摘要
目的:观察针灸对不明原因性不孕症患者甲状腺自身抗体(TPO-Ab、TG-Ab)水平的影响。方法:选取2016年1月至2016年9月在开封市医学科学研究所生殖中心就诊的不明原因性不孕症患者192例为研究组,另选取同期112例有正常妊娠史备孕健康妇女为对照组。采用化学发光免疫分析仪测定两组患者治疗前后血清中的TPO-Ab、TG-Ab含量,探讨针灸对不明原因性不孕症患者甲状腺自身抗体的影响。结果:研究组ATA阳性率、TG-Ab阳性率、TPO-Ab阳性率与对照组比较,差异有统计学意义(P<0.01);观察研究组治疗前后甲状腺自身抗体的变化,治疗后TG-Ab水平降低(t=5.378,P<0.01),TPO-Ab水平降低(t=10.017,P<0.01),与治疗前比较,差异有统计学意义。结论:ATA阳性与不明原因性不孕症存在一定的相关性,针灸对患者TPO-Ab、TG-Ab有改善作用。
Objective：To observe the influence of acupuncture and moxibustion on TPO-Ab and TG-Ab levels of antithyroid anti- body of patients with unnexplained infertility. Methods ： One hundred and ninety-two women patients with unnexplained infertility wbo were treated in Reproductive Center of Kaifeng City Institute of Medical Sciences between Jan. 2016 and Sept. 2016 were cho- sen into the research group. In the same period, 112 healthy women with normal pregnancy history were selected into the control group. By using chemiluminescence immunoanalyzer, the contents of TPO-Ab and TG-Ab in blood serum of the research group and the control group before and after the treatment were measured to explore observe the influence of acupuncture and moxibustion on antithyroid antibody of patients with unnexplained infertility. Results ： The differences in positive rates of ATA, TG-Ab and TPO-Ab between the research group and the control group were. significantly （ P 〈 0.01 ）. The differences in changes of antithyroid antibod- y before and after the treatment,the decreased TG-Ab level（t = 5. 378 ,P 〈0.01 ,and TPO-Ab（t = 10. 017,P 〈0.01 ） after the treatment were statistically significant. Conclusion ：There is a certain correlation between ATA positive and unexplained infertility. Acupuncture and moxibustion can improve the patients＇ TPO-Ab and TG-Ab.
出处
《河南中医》
2018年第1期125-127,共3页
Henan Traditional Chinese Medicine
基金
开封市科技创新项目(编号:1407010)
