摘要
目的综合分析特拉唑嗪联合氨氯地平片在肾性高血压的应用价值。方法选取在本院2014年10月~2017年3月期间收治的36例肾性高血压患者,按照入院顺序随机分为实验组(应用氨氯地平片联合特拉唑嗪治疗方法,18例)与对照组(应用氨氯地平片治疗方法,18例)。采用SPSS20.0统计学软件进行统计学分析两组患者的收缩压水平、舒张压水平、尿蛋白水平、肾功能指标(尿素氮、血肌酐)以及临床治疗总有效率等参数指标。结果 (1)治疗前,两组患者的收缩压水平、舒张压水平、尿蛋白水平比较差异无统计学意义(P>0.05);治疗后,实验组患者的收缩压水平、舒张压水平、尿蛋白水平显著优于对照组患者(P<0.05);(2)治疗前,两组患者的尿素氮、血肌酐等肾功能指标比较无统计学意义(P>0.05);治疗后,实验组患者的尿素氮、血肌酐等肾功能指标显著优于对照组患者(P<0.05);(3)实验组临床治疗总有效率显著高于对照组患者(P<0.05)。结论特拉唑嗪在肾性高血压的应用价值比较高。
Objective To analyze the application value of trazozine in renal hypertension synthetically. Methods Thirty-six patients with renal hypertension in our hospital from October 2014 to March 2017 were selected and they were randomly divided into experimental group （application of amlodipine with terazosin,18 cases） and control group （application of amlodipine,18 cases）.The systolic blood pressure level,diastolic blood pressure level,urinary protein level,renal function index （urea nitrogen,blood creatinine） and total effective rate of two groups of patients were analyzed by SPSS20.0 statistical software. Results （1） Before treatment,the systolic blood pressure levels,diastolic blood pressure levels and urinary protein levels in the two groups were not statistically significant （P 〉 0.05）.Afier treatment,the systolic blood pressure level,diastolic blood pressure level and urinary protein level of the experimental group were significantly better than those in the control group （P 〈 0.05）.（2） Before treatment,the renal function indexes,such as urea nitrogen and blood creatinine,were not statistically significant in the two groups （P 〉 0.05）. After treatment,the renal function indexes such as urea nitrogen and blood creatinine in the experimental group were significantly better than those in the control group （P 〈 0.05）.（3） the total effective rate of clinical treatment in the experimental group was significantly higher than that of the control group （P 〈 0.05）. Conclusion Trazozine has high application value in renal hypertension.
出处
《中国医药科学》
2018年第1期91-94,共4页
China Medicine And Pharmacy
关键词
特拉唑嗪
肾性高血压
应用价值
氨氯地平片
Terazosin
Renal hypertension
Application value
Amlodipine tablet
