摘要
目的:观察和分析经期阿奇霉素序贯治疗慢性附件炎的临床疗效。方法:选取2014年3月—2016年3月我院收治的126例慢性附件炎患者,根据住院顺序均分为实验组和对照组,每组各63例。实验组患者使用经期阿奇霉素序贯治疗,而对照组患者使用阿奇霉素联合甲硝唑静脉滴注治疗,对比两组患者的治疗有效率、不良反应率以及复发情况。结果:实验组患者治疗的总有效率为98.41%,对照组患者治疗的总有效率为85.71%,两组患者间的差异存在统计学意义(P<0.05)。实验组患者总不良反应率为6.35%,对照组患者总不良反应率为23.81%,两组患者间的差异存在统计学意义(P<0.05)。在患者治疗半年之后,实验组患者的复发率为1.59%,对照组患者的复发率为3.14%,两组患者复发率间的差异没有统计学意义(P>0.05)。结论:对于慢性附件炎,在患者经期进行阿奇霉素序贯治疗的效果更好,并且发生不良反应也少,在临床上值得推广。
Objective： The clinical effect of the sequential treatment of azithromycin on chronic adnexitis was analyzed. Methods： 126 patients with chronic adnexitis admitted in our hospital from March 2014-March 2016 were divided into the experimental group and the control group according to the order of hospitalization, with 63 cases in each group. The patients in the experimental group were treated with azithromycin during the menstrual period, while the control group was treated with Azithromycin combined with metronidazole intravenous drip. The effective rate, the adverse reaction rate and the recurrence rate of the two groups were compared. Results： The total effective rate of the patients in the experimental group was 98.41%, and the total effective rate of the control group was 85.71%. The difference between the two groups was statistically significant（P〈0.05）. The total adverse reaction rate of the patients in the experimental group was 6.35%, and the total adverse reaction rate was 23.81% in the control group. The difference between the two groups was statistically significant（P〈0.05）. After six months＇ treatment, the recurrence rate of the experimental group was 1.59%, and the recurrence rate of the control group was 3.14%. There was no significant difference in recurrence rate between the two groups（P〉0.05）. Conclusion： For chronic annexitis, Azithromycin sequential therapy in patients with menstrual period is very effective, and there are few adverse reactions. It is worth promoting in clinical practice.
出处
《药品评价》
CAS
2018年第2期54-56,共3页
Drug Evaluation
关键词
经期
阿奇霉素
序贯治疗
慢性附件炎
临床疗效
Period
Azithromycin
Sequential Therapy
Chronic Adnexitis
Clinical Efficacy
