摘要
目的观察益气活血、温阳利水方治疗收缩性心力衰竭病人的临床疗效。方法将60例气虚血瘀,阳虚水泛型收缩性心力衰竭病人随机分为试验组和对照组,对照组予以常规西药治疗,试验组在对照组基础上加用益气活血、温阳利水方,疗程4周,观察治疗前后病人血浆N末端脑钠肽原(NT-proBNP)浓度、左室射血分数(LVEF)、心功能分级变化及中医证候疗效改善情况。结果治疗后两组病人LVEF均明显提高,血浆NT-proBNP明显减低,差异有统计学意义(P<0.05);试验组治疗后LVEF较对照组明显提高(P<0.05);试验组心功能疗效、中医证候效总有效率高于对照组(P<0.05)。结论在常规西药治疗基础上联合应用益气活血、温阳利水方治疗慢性收缩性心力衰竭病人临床疗效显著。
Objective To observe the clinical effect of Yiqi Huoxue Wenyang Lishui prescription （YHWLP）in the treatment of systolicheart failure.Methods Sixty patients with systolic heart failure and traditional Chinese medicine （TCM）syndrome of qi deficiencyand blood stagnation,yang deficiency and water overflow were randomly divided into two groups：control group treated with routinetreatment,and treatment group treated with routine treatment plus YHWLP for 4 weeks.The levels of plasma N terminal pro Btype natriuretic peptide （NT proBNP）,left ventricular ejection fraction （LVEF）,cardiac function classification,and TCM symptom improvementwere observed before and after treatment.Results After treatment,LVEF,cardiac function classification,and the improvementof TCM symptom were significantly improved in two groups,which was better in treatment group than that in control group （P 〈0.05）.The levels of plasma NT proBNP were decreased in two groups after treatment,which were lower in treatment group than thatin control group （P 〈0.05）.Conclusion YHWLP and routine treatment has a significant clinical effect in patients with systolic heartfailure.
出处
《中西医结合心脑血管病杂志》
2018年第2期134-136,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
北京市科技计划课题项目(No.Z141107002514151)
北京中医药大学校级课题项目(No.2015-JYB-JSMS101)
关键词
收缩性心力衰竭
气虚血瘀
阳虚水泛型
益气活血温阳利水方
N末端脑钠肽原
systolic heart failure
qi deficiency and blood stagnation
yang deficiency and water overflow
Yiqi Huoxue Wenyang Lishuiprescription
N terminal pro B type natriuretic peptide
