摘要
目的通过分析乳腺癌患者的临床病理特征,探索前哨淋巴结(SLN)转移的高危因素,为腋窝淋巴结的个体化处理提供依据。方法回顾性分析郑州大学第三附属医院乳腺科2015-05—2017-05间收治的120例行前哨淋巴结活检术(SLNB)患者的临床病理资料。采用单因素分析及多因素Logistic回归分析方法,研究各项临床变量与早期乳腺癌腋窝SLN转移的关系。结果单因素分析显示,脉管浸润、组织学分级等变量在SLN转移的差异性具有统计学意义(P<0.05)。将单因素分析有统计学差异的因素继续开展多因素Logistic回归分析显示,脉管浸润是SLN转移的独立危险因素(OR=7.000,P=0.001)。结论脉管浸润可作为预测早期乳腺癌SLN转移的独立危险因素。
Objective To analyze the clinical and pathological parameters that may affect the sentinel lymph node( SLN) metastasis in early-stage breast cancer,to analyze the sentinel lymph node status and the risk factors for SLN metastasis in early breast cancer patients and provide a reference for the development of a more rational individualized treatment program. Methods The clinical and pathological data of 120 breast cancer patients who underwent sentinel lymph node biopsy( SLNB) in the Third Affiliated hospital of zhengzhou University between may 2015 to may 2017 were collected. The relations of the clinicopathologic factors with SLN metastasis were determined by univariate and multivariate Logistic regression analysis. We used the SPSS 22. 0 as the statistics software in this study,a probability level of < 0. 05 was considered statistically significant. Results Univariate analysis showed that histological grade and vessel invasion were related to SLN metastasis( all P <0. 05); Logistic regression analysis identified that vessel invasion( OR = 7. 000,P = 0. 001) was independent risk factors for SLN metastasis.Conclusion Vascular invasion can be used as independent variables to predict SLN metastasis in breast cancer patients.
出处
《河南外科学杂志》
2018年第1期7-9,共3页
Henan Journal of Surgery
关键词
乳腺癌
前哨淋巴结
危险因素
Early breast cancer
Sentinel lymph node
Risk factors
