摘要
高精密度的水凝胶微结构有利于更好地模拟生物体内微环境,双光子聚合微加工有望加工出任意形貌的高精密度水凝胶微结构.为了改善微结构的刚性,调节光刻胶的成分,加工了3种不同种类的微结构,优化后的光刻胶用于后续微结构的加工,研究了正加工和倒加工的差异.进一步研究了激光扫描速度对加工时间的影响.结果表明,适当提高聚合物刚性、采用倒加工以及适当提高扫描速度可以高效地加工出高精密度的水凝胶微结构.
Hydrogel microstructure with high precision could better simulate the microenvironment in vivo. Two-photon polymerization microfabrication （TPPM） is expected to fabricate arbitrary hydrogel microstructure with highprecision. To improve the stiffness of microstructure,the composition of photoresist was tuned to fabricate threekinds of microstructures. The optimal photoresist was chosen to fabricate the subsequent microstructures. The differ-ence between up-down and inversion processing was investigated. Furthermore,the impact of writing speed on proc-essing time was studied. The results show that increasing polymer rigidity,adopting inversion processing and enhanc-ing writing speed together can efficiently fabricate hydrogel microstructures with high precision.
出处
《天津大学学报（自然科学与工程技术版）》
EI
CSCD
北大核心
2018年第2期210-214,共5页
Journal of Tianjin University：Science and Technology
基金
国家自然科学基金资助项目(31371014)~~
关键词
双光子聚合微加工
高精密度
PEG
水凝胶微结构
two-photon polymerization microfabrication（TPPM）
high precision
PEG
hydrogel microstructure
