摘要
目的探讨肝硬化失代偿期患者述情障碍与生存质量的关系。方法选择120例肝硬化失代偿期患者为研究对象,其中述情障碍组[多伦多述情障碍量表(TAS-20)≥61分]和无述情障碍组(TAS-20<60分)各60例。使用WHO生存质量测定量表简表(WHOQOL-BREF)评估并比较两组患者的生存质量,并对TAS-20与WHOQOL-BREF的关系作Pearson相关分析。结果述情障碍组TAS-20总分以及情感辨别不能(DIF)、情感描述不能(DDF)、外向性思维(EOT)等因子评分均明显高于无述情障碍组(均P<0.05)。述情障碍组生存质量评价、健康状况满意度、生理领域、心理领域的评分均明显低于无述情障碍组(均P<0.05);但在社会关系、环境等领域评分比较,差异均无统计学意义(均P>0.05)。肝硬化失代偿期患者WHOQOL-BREF总体自评分与TAS-20总分及DIF、DDF、EOT等因子评分均呈负相关(r=-0.452、-3.953、-0.264和-0.332,均P<0.05);生理领域与TAS-20总分及DIF、DDF、EOT等因子评分均呈负相关(r=-0.421、-0.256、-0.322和-0.228,均P<0.05);心理领域与TAS-20总分、DIF因子评分均呈负相关(r=-0.198、-0.226,均P<0.05);社会关系领域与EOT均呈负相关(r=-0.229,均P<0.05);环境领域与TAS-20总分、EOT因子评分均呈正相关(r=0.169、0.255,均P<0.05)。结论肝硬化失代偿期患者发生述情障碍,可明显降低患者的生存质量。述情障碍越严重则生存质量越低。
Objective To investigate the relationship between alexithymia and the quality of life in patients with liver cirrhosis at decompensation stages. Methods One hundred and twenty patients with liver cirrhosis at decompensation stages were enrolled in the study. According to scores of Toronto Alexithymia Scale(TAS-20), patients were divided into the alexithymia group(TAS-20≥61) and non-alexithmia group(TAS-20 <60). The quality of life was evaluated by WHOQOL-BREF. The relationship between TAS-20 score and WHOQOL-BREF score was analyzed by Pearson correlation analysis. Results The total scores of TAS-20 and the scores of emotion identification(DIF), emotional description(DDF) and extroverted thinking in the alexithymia group were higher than those in the non-alexithmia group(P<0.05). The scores of quality of life, satisfaction of health status, physiological domain, and psychological domain in the alexithymia group were lower than those in the no-alexithmia group. There were no significant differences between two groups in scores of social relations, environment and other domains.The total scores of WHOQOL-BREF were negatively correlated with TAS-20 total score, DIF, DDF and EOT scores in patients with liver cirrhosis at decompensation stages(r=-0.452,-3.953,-0.264,-0.332, P<0.05). The scores in physiological domain were negatively correlated with total TAS-20 scores, DIF, DDF, EOT scores(r=-0.421,-0.256,-0.322,-0.228, P<0.05). The scores in psychological domain were negatively correlated with TAS-20 total scores and DIF scores(r=-0.198,-0.226, P<0.05).The scores in social relations were negatively correlated with EOT scores(r=-0.229, P<0.05). The scores in environment domain were negatively correlated with TAS-20 total scores and EOT score(r=0.169, 0.255, P<0.05). Conclusion The alexithymia has negative effect on the quality of life in patients with liver cirrhosis patients at decompensation stage.
出处
《浙江医学》
CAS
2018年第4期368-370,共3页
Zhejiang Medical Journal
基金
浙江省教育厅科研项目(Y201328800)
关键词
肝硬化
情绪障碍
生存质量
Liver cirrhosis
Mood disorders
Quality of life
