摘要
目的影响胶质瘤患者生存期的相关因素。方法回顾性分析西京医院神经外科2010年1月至2014年1月收治的200名Ⅱ~Ⅳ级胶质瘤患者,通过翻阅病历及电话随访的方式获取患者资料,使用SPSS 19.0统计学软件进行多因素的生存分析。结果年龄大于60岁、中性粒细胞与淋巴细胞比值大于4为影响预后的危险因素,替莫唑胺、尼莫司汀(福莫司汀)、放疗、同步放化疗是影响预后的保护因素。结论年龄大于60岁、中性粒细胞与淋巴细胞比值大于4均提示胶质瘤患者预后不良,化疗、放疗和同步放化疗方案对各级别胶质瘤患者生存期有一定改善。
Objective The factors affecting the survival time of patients with ghonm were discussed. Methods A total of 200 patients with Grade II - IV glioma from January 2010 to January 2014 in Xijing Hospital were analyzed retrospectively. The data were obtained from the medical records and telephone follow-up data. Multivariate survival analysis was conducted by SPSS 19. 0 statistical software. Results Age older than 60 years, ratio of neutmphils to lymphocytes 〉 4 were the risk factors of the prognosis. Temozolomide, Nimustine （Fotemustine）, radiotherapy, simultaneous radiotherapy and chemotherapy were the protective factors of the prognosis. Conclusion Age over 60 years and ratio of neutrophils to lymphocytes 〉 4 suggest that glioma patients have a poor prognosis. Chemotherapy, radiotherapy and concurrent chemoradiotherapy have a certain improvement in survival time of patients with gliomas.
出处
《中华神经外科疾病研究杂志》
CAS
2018年第1期35-38,共4页
Chinese Journal of Neurosurgical Disease Research
关键词
胶质瘤
预后
Clioma
Prognosis
