摘要
目的观察纤维支气管镜联合肺泡灌洗术治疗重症肺部感染患者的临床疗效。方法选择2016年2月-2017年2月于医院治疗的重症肺部感染患者128例,分为试验组和对照组,各64例,试验组进行纤维支气管镜联合肺泡灌洗术治疗,对照组采用常规治疗。治疗前后检测各项血气指标并在治疗10天后评价治疗效果,评估纤维支气管镜联合肺泡灌洗术治疗重症肺部感染患者的临床疗效。结果试验组疗效优于对照组(P<0.001);治疗前两组各项血气指标,差异无统计学意义;试验组治疗后血氧分压(PaO2)、二氧化碳分压(PaCO2)、酸碱度(pH)、血氧饱和度(SpO2)、气道阻力、平均动脉压(MAP)分别为(86.49±8.70)mmHg、(42.19±4.06)mmHg、(4.14±0.86)、(98.07±6.75)%、(62.80±2.93)mmHg、(6.82±2.10)cm Hg优于对照组(P<0.001)。结论纤维支气管镜联合肺泡灌洗术能有效治疗重症肺部感染患者,疗效优于常规治疗。
OBJECTIVE To observe the clinical effect of fiber bronchoscope combined with bronchoalveolar lavage in treating patients with severe pulmonary infections.METHODS A total of 128 cases of patients with severe pulmo- nary infections treated in our hospital from Feb. 2016 to Feb. 2017 were selected, and were randomly divided into experimental group and control group, with 64 cases in each group. Patients in experimental group were treated with fiber bronchoscope combined with bronchoalveolar lavage, and in control group were treated with convention- al therapy. Before and after treatment, the indexes of blood gas analysis were recorded and the therapeutic effect was assessed after 10 days of treatment. The clinical effects of fiber bronchoscope combined with broncboalveolar lavage in treating patients with severe pulmonary infections were evaluated.RESULTS The clinical effect of the ex- perimental group was better than that of the control group（P〉0.001）.Before treatment, there was no significant difference between the two groups in blood gas index. After treatment, the partial pressure of oxygen（PaO2 ）, partial pressure of carbon dioxide（PaCO2）, pH value（pH）, blood oxygen saturation（SpO2 ）, mean arterial pres- sure（MAP）, and airway resistance of experimental group were （86.49 8.70） mmHg, （42.19±4.06） mmHg, （4.14±0.86）, （98.07±6.75）%, （62.80±2.93）mmHg, and （6.82±2.10）cm Hg, respectively, which were sig- nificantly better than（67.24± 8.96） mmHg, （47.54±3.82） mmHg, （6.58± 1.24）, （84.21 ± 8.99） %, （72.16± 3.18） mmHg, and（9.17 ± 2.52 ） cm H g （ P 〈 0.001 ）. CONCLUSION Fiber bronchoscopy combined with bronchoalveolar lavage is effective in the treatment of patients with severe pulmonary infections, and its curative effect is better than conventional treatment.
作者
董朝晖
谢艳萍
陈志冬
徐巍
钟莉
DONG Zhao-hui;XIE Yan ping;CHEN Zhi-dong;XU Wei;ZHONG Li(The First People＇s Hospital of Huzhou, Huzhou, Zhejiang 313000, China)
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2018年第3期364-366,397,共4页
Chinese Journal of Nosocomiology
基金
浙江省公益基金资助项目(2017C33178)
关键词
纤维支气管镜
肺泡灌洗术
重症肺部感染
FIBER bronchoscope
BRONCHOALVEOLAR lavage
SEVERE pulmonary infection
