摘要
化疗药物的心脏毒性越来越受到关注。在临床实践中,可以通过降低药物剂量、调整给药管理和使用低毒剂型等优化化疗方案对策降低心脏毒性反应的发生率和严重程度。心脏保护剂的应用也非常重要,目前常用的药物包括右丙亚胺、心血管药物和中药制剂等,但这些药物作为心脏保护剂的应用具有局限性,且其有效性和安全性尚需要进一步验证。
The cardiotoxicity of chemotherapeutic drugs is receiving more and more attention. The incidence and severity of cardiotoxicity can be reduced by methods such as reducing the dose of drugs, adjusting administration, and using low toxic drugs in clinical practice. Besides, app Lncation of cardioprotective agents is very important and agents including cardiovascular ones, dexrazoxane as well as Chinese medicine preparations are commonly used currently. However, effects of these agents used for cardioprotection during chemotherapy are limited, and their safety needs further verification.
出处
《中国癌症杂志》
CAS
CSCD
北大核心
2018年第1期75-80,共6页
China Oncology
基金
国家自然科学基金项目(81473498)
