摘要
目的对采用FOLFOX6化疗方案的消化道癌症患者在接受化疗期间时产生的各种症状进行评估分类，并探讨各症状群的影响因素。方法本研究采取问卷调查法，采取便利抽样方法选取某三级甲等综合医院化疗科100例患者进行一般资料、安德森症状评估表和社会支持评定量表进行调查分析。结果患者各症状中食欲不振的严重程度及出现频率最高，对生活乐趣的干扰最大，主成分分析提取3种类型症状群即胃肠道症状群、躯体化症状群和情感精神症状群；回归分析显示随着化疗周期增多，胃肠道症状及躯体化症状逐渐加重，增加患者主观支持可以明显降低其精神情感症状的发生率。结论针对各症状的严重程度、症状群分类及各种症状群影响因素制定适当护理措施，以提高患者对化疗药物的耐受程度。
Objective To investigate the status and influencing factors of symptom clusters in patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy. Methods Totally 100 patients with gastrointestinal cancer receiving FOLFOX6 chemotherapy were investigated using MD. Anderson Symptom Inventory-Chinese （MDASI-C） and Social Support Rating Scale （SSRS）. Results The top incidences and severity of symptoms was lack of appetite. Exploratory factor analysis showed three main symptom clusters： gastrointestinal symptom clusters, physical symptom clusters and mental symptom clusters. The number of courses of chemotherapy was the influencing factor of gastrointestinal symptom clusters, physical symptom clusters. For mental symptom clusters, social support was the influencing factor. Conclusions Patients with gastrointestinal cancer suffer from multiple symptoms during FOLFOX6 chemotherapy. The results are good for establishing early predictions of symptoms and providing scientific evidence for the interventions of symptoms clusters.
出处
《中国实用护理杂志》
2018年第5期321-325,共5页
Chinese Journal of Practical Nursing
基金
山东省医药卫生科技发展计划（2015WS0301）
关键词
症状群
化疗
消化道癌症
影响因素
Symptoms clusters
Chemotherapy
Gastrointestinal cancer
Influencing factor
