症状性颈动脉狭窄支架置入术患者不同疗效的术前超声指标分析被引量：7

Preoperative ultrasonographic parameters in symptomatic carotid artery stenosis patients with different curative effects of stenting

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摘要目的探讨症状性颈动脉狭窄支架置入术患者不同疗效的术前超声指标的差异及其与年龄的关系。方法选择2008年1月~2016年6月在河南科技大学第一附属医院住院的症状性颈动脉狭窄支架置入术患者57例,根据年龄分为青年组7例,中年组25例,老年组25例。又根据术后美国国立卫生研究院卒中量表评分改善率≥75%为显效组18例,25%~74%为有效组33例,<25%为无效组6例。比较和分析各组患者术前3d内颈动脉超声指标的差异性。结果显效组、有效组及无效组不稳定斑块积分比值、斑块最大偏心比值、狭窄处峰值流速、搏动指数、阻力指数、颈动脉僵硬度指数、扩张系数及顺应系数比较,差异有统计学意义(P<0.01)。老年组颈动脉僵硬度指数明显高于青年组和中年组(3.762±1.048 vs 2.313±0.409,2.707±0.656,P<0.01)。颈动脉僵硬度与年龄呈正相关(r=0.670,P=0.000),且两者存在线性回归方程(y=0.075x-1.537,R2=0.448,F=44.727,P=0.000)。结论不同疗效患者术前颈动脉不稳定斑块积分比值、斑块最大偏心比值、狭窄处峰值流速、阻力指数、搏动指数、颈动脉僵硬度指数、扩张系数及顺应系数存在差异,颈动脉僵硬度指数与患者年龄存在线性关系。 Objective To study the preoperative ultrasonographic parameters and their relationship with age in symptomatic CAS patients with different curative effects of stenting. Methods Fiftyseven symptomatic CAS patients admitted to our hospital for stenting were divided into young age group （n=7）, middle age group （n = 25）, old age group （n = 25） according to their age, and into very good curative effect group （n=18）,good curative effect group （n=33） and no curative effect group （n=6） according to their postoperative NIHSS score. The carotid ultrasonographic parameters in different groups were compared and analyzed within 3 clays before operation. Results A significant difference was found in the ratio of UPT, maximal ER of plaques, PV of stenosis, PI, resistance index （RI）, carotid artery stiffness index （SI）, distensibility coefficient （Dc） and compli ance coefficient （Cc） in different curative effect groups （P〈0.01）. The carotid artery SI was sig nificantly higher in old age group than in young age group and middle age group （P〈0.01）. A linear regression equation was established between carotid stiffness and age （y=0. 075x-1. 537, R2 = 0. 448, F= 44. 727, P = 0. 000）. Conclusion The ratio of UPT, maximal ER of plaques, PV of stenosis, PI, RI, carotid artery SI,Dc and Cc are different in patients with different curative effects of stenting,and a linear relationship is found between carotid artery SI and age of patients.