摘要
目的:探讨应用碘佛醇行上消化道造影对先天性肥厚性幽门狭窄诊断的意义。方法:选取2014年6月至2016年12月41例临床症状可疑先天性肥厚性幽门狭窄(congenital hypertrophic pyloric stenosis,chps)的新生儿,应用碘佛醇行上消化道造影及超声检查,以术后及出院诊断作为金标准,对比分析两者诊断的灵敏度及特异度;记录碘佛醇行上消化道造影后可能出现的过敏及其他不良反应,随机抽取部分碘佛醇行上消化道造影患儿,进行造影前后24 h肾功能检查,分析碘佛醇行上消化道造影对新生儿肾功能是否有影响。结果:碘佛醇行上消化道造影对先天性肥厚性幽门狭窄诊断的灵敏度为100.0%,超声检查的灵敏度为85.0%;碘佛醇行上消化道造影对先天性肥厚性幽门狭窄诊断的特异度为96.0%,超声检查的特异度为89.0%,差异无统计意义(P>0.05),碘佛醇行上消化道造影后仅有1例轻度恶心,造影24 h前后血尿素及肌酐对比,差异无统计学意义(P>0.05)。结论:碘佛醇行上消化道造影可以作为诊断先天性肥厚性幽门狭窄的诊断依据,未见明显不良反应。
Objective：to explore the significance of upper gastrointestinal contrast with ioversol in the diagnosis of congenital hypertrophic pyloric stenosis（CHPS）.Methods：41 neonates with clinically suspected CHPS from June 2014 to December 2016 were chosen and performed upper gastrointestinal contrast with ioversol and ultrasonography,with sensitivity and specificity contrasted and analyzed based on postoperative and discharge diagnosis and the allergy and other adverse reactions recorded.Some neonates who were performed upper gastrointestinal contrast with ioversol were randomly chosen,with their renal function 24 hours before and after the contrast examined and the effect of it on the renal function in the neonates analyzed.Results：The sensitivity of upper gastrointestinal contrast with ioversol in diagnosing CHPS was 100 % while the sensitivity of ultrasonography was 85 %;the specificity of upper gastrointestinal contrast with ioversol in diagnosing CHPS was 96% while the sensitivity of ultrasonography was 89%,the difference being not significant（P〉0.05）.There were only 1 case of mild nausea and there was no difference in urea and creatinine before and after 24 hours of contrast（P〉0.05）.Conclusion：Upper gastrointestinal contrast with ioversol can be used as the basis for the diagnosis of CHPS without obvious adverse effects.
出处
《包头医学院学报》
CAS
2018年第1期19-20,23,共3页
Journal of Baotou Medical College
关键词
新生儿
上消化道造影
幽门狭窄
碘佛醇
The newborn
Upper gastrointestinal contrast
Pyloric stenosis
Ioversol
