5Hsu YW, Cortinez LI, Robert son KM, et al. Dexmedetomidine pharmacodynamics: part I. crossover comparison of the respir atory effects of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology, 2004,101:1066-1076.
6Cortinez LI, Hsu YW, Sum-Ping ST, et al. Dexmedetomidine pharmacodynamics.Part II. Crossover comparison of the anal- gesic effect of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology, 2004,101 : 1077-1083.
7Murrell JC, Hellebrekers LG. Medetomidine and dexmedeto- midine:a review of cardiovascular effects and antinociceptive properties in the dog. Vet Anaesth Analg,2005,32:117-127.
8Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anes- thesiology, 2000,93 : 382-394.
9Coull JT, Jones M, Egan T, et al. Attentional effects of nora- drenaline vary with arousal level: selective activation of tha- lamic pulvinar in humans. Neuro Image, 2004,22:315-322.
10Cheung CW, Ying CL, Chiu WK, et al. A comparison of dexmedetomidine and midazolam for sedation in third molar surgery. Anaesthesia, 2007,62 : 1132-1138.