摘要
目的分析快速检测试剂(RDT)推广前后石家庄市疟疾检测情况,探讨消除后阶段监测工作,为措施制定提供依据。方法从寄生虫防治信息管理系统收集2015年-2016年各县(市)区血检月报表和疟疾个案信息,对血检情况进行整理分析。结果 2015年完成血涂片5 899份,检测结果阳性率为0.49%(29/5 899);2016年完成血涂片1 572份,快速检测试纸(RDTs)1 282份,阳性率分别为2.99%(47/1 572)、4.13%(53/1 282)。市区检测阳性率显著高于平原县和山区县。血涂片镜检的敏感度为88.68%,RDT的敏感度为100.00%。经一致性检验,镜检、RDT的Kappa值为0.66,两方法检测结果中度一致(P<0.01)。结论降低发热患者血涂片镜检数量要求,能大幅提升血检效率,符合当前输入性疟疾疫情形势。RDT敏感度高,对技术要求低,在疟疾消除后阶段推广RDT检测,有利于医疗机构疟疾病例的发现。
Objective To analyze the results of malaria before and after the application of rapid detection reagent（ RDT） in Shijiazhuang,and explore malaria surveillance in post-elimination period,so as to provide basis for formulating measures.Methods Blood examination reports and case reports monthly from the Parasite Control Information Management System were collected,and blood examination data was analyzed. Results 5 899 blood smears were collected in 2015,the positive rate was0. 49%（ 29/5 899）; 1 572 blood smears and 1 282 RDTs were collected in 2016,the positive rates were 2. 99%（ 47/1 572）,4. 13%（ 53/1 282）. The positive rates in urban district was obvious higher than plain county and mountain county. The sensitivity of blood smear was 88. 68%,and that of RDT was 100. 00%. Kappa value between blood smear and RDT was 0. 66,and the two methods were moderately consistent（ P 〈 0. 01）. Conclusion Reducing the number of smear microscopy in fever patients can significantly improve the efficiency of blood tests,which is in line with the current situation of imported malaria epidemic situation. RDT has high sensitivity,low technical requirements,and the promotion of RDT detection in the post-malaria elimination phase is conducive to the discovery of malaria cases in medical institutions.
出处
《中国卫生检验杂志》
CAS
2018年第1期96-97,101,共3页
Chinese Journal of Health Laboratory Technology
基金
河北出入境检验检疫局科研项目(HE2017K012)
关键词
疟疾
消除后阶段
快速检测试剂
镜检
敏感度
Malaria
Post-elimination period
Rapid detection reagent
Microscopy
Sensitivity
