摘要
目的了解西安交通大学第一附属医院呼吸道感染患儿肺炎支原体(MP)的感染情况,为临床儿科的早期诊断和治疗提供帮助。方法收集西安交通大学第一附属医院2014年1月至2015年12月3 216例门诊呼吸道感染患病儿(≤12岁)血清标本进行MP-IgM抗体检测,并进行统计学分析。结果在3 216例门诊患儿中共检出MP-IgM阳性病例969例,总阳性率为30.1%。2014年和2015年MP-IgM阳性率分别为24.8%和37.2%,经比较差异具有统计学意义(χ~2=58.222,P<0.001)。不同季节的MP-IgM阳性检出率比较差异具有统计学意义(χ~2=18.795,P<0.001)。不同年龄段间总体的MP-IgM阳性检出率比较差异具有统计学意义(χ~2=26.413,P<0.001)。男性患儿(1 760例)MP-IgM阳性率为26.0%,女性患儿(1 456例)MP-IgM阳性率为35.1%,女性患儿MP-IgM的阳性率明显高于男性患儿(χ~2=31.161,P<0.001)。结论小儿MP的感染呈逐年递增趋势,全年均可发病,其中以秋、冬季高发;多发生于学龄前和学龄期儿童,存在性别差异。3~12岁儿童为高危人群,应引起高度重视,做好预防工作。
Objective To understand the prevalence of mycoplasma pneumoniae（MP）in children with respiratory infection in First Affiliated Hospital of Xi＇an Jiaotong University and to provide help for early diagnosis and treatment in clinical pediatric.Methods Serum samples of 3 216 outpatient children（≤12 years old）with respiratory tract infection visiting First Affiliated Hospital of Xi＇an Jiaotong University from January 2014 to December 2015 were collected,and MP-IgM antibodies were detected in serum samples and statistical analysis was done.Results A total of 969 MP-IgM positive cases were detected in 3 216 outpatients and total positive rate was 30.1%.The positive rate of MP-IgM in 2014 and in 2015 were 24.8% and 37.2%respectively,and the difference was statistically significant（χ~2=58.222,P〈0.001）.Difference in positive rate of MP-IgM in various seasons was statistically significant（χ~2=18.795,P〈0.001）.There was significant difference in total positive rate of MP-IgM in different age groups（χ~2=26.413,P〈0.001）.Positive rate of MP-IgM in male patients（1 760 cases）was 26.0%,and that in female patients（1 456 cases）was 35.1%.Positive rate of MP-IgM in female patients was significantly higher than that in male patients（χ~2=31.161,P〈0.001）.ConclusionIncidence of MP infection in children shows an increasing trend year by year,which can happen throughout the year with high incidence in autumn and winter.It mostly occurs in preschool and school-aged children,and incidence has gender difference.Children at 3-12 years old are high-risk groups who should be paid with attention and prevention work should be done well.
出处
《中国妇幼健康研究》
2017年第12期1645-1647,共3页
Chinese Journal of Woman and Child Health Research
基金
国家自然科学基金资助项目(编号:81201326)
关键词
肺炎支原体
MP-IgM抗体
呼吸道感染
儿童
mycoplasma pneumonia （MP）
MP-IgM antibody
respiratory tract infection
children
