摘要
目的评估酚妥拉明联合多巴胺治疗42例难治性心力衰竭的临床疗效。方法选取84例难治性心力衰竭患者作为研究对象,按随机盲选法分为两组,对照组42例给予常规治疗,观察组42例给予酚妥拉明联合多巴胺治疗,比较两组临床治疗效果。结果治疗前心率、收缩压、舒张压两组比较差异未见统计学意义(P>0.05);治疗后,两组三项指标呈降低趋势,观察组降低趋势更显著(P<0.05);治疗前后左室射学分数,两组比较差异未见统计学意义(P>0.05)。观察组治疗总有效率为95.24%,高于对照组的71.43%,差异有统计学意义(P<0.05)。结论难治性心力衰竭患者给予酚妥拉明联合多巴胺治疗,疗效显著,值得采纳应用。
Objective To evaluate the clinical efficacy of phentolamine combined with dopamine in the treatment of 42 patients with refractory heart failure.Methods Eighty-four cases with refractory heart failure were randomly divided into two groups,42 cases in control group were given conventional treatment,42 cases in observation group were treated with phentolamine and dopamine treatment,the clinical efficacy of the two groups were compared and assessed.Results Before treatment,the heart rate,systolic blood pressure and diastolic blood pressure in two groups had no statistically significant difference(P〈0.05),but the three indicators were decreased after treatment,and the observation group decreased more significantly compared with the control group(P〉0.05); the left ventricular ejection fraction had no statistically significant difference in two groups after treatment(P〈0.05).The total effective rate in the observation group was 95.24%,which was significantly higher than that(71.43%) in the control group and the difference was statistically significant(P〉0.05).Conclusions Phentolamine combined with dopamine has a significant effect on patients with refractony heart failure and is worthy of adoption.
出处
《临床医学》
CAS
2017年第10期89-90,共2页
Clinical Medicine
关键词
酚妥拉明
多巴胺
难治性心力衰竭
Phentolamine
Dopamine
Refractory heart failure
Clinical efficacy