摘要
目的探讨艾司西酞普兰联合行为激活疗法治疗抑郁障碍的临床效果。方法选取2015年9月—2016年6月于福建省三明市医学会收治的抑郁障碍患者80例,采用随机数字表法分为对照组(n=40)和观察组(n=40)。对照组患者均予以草酸艾司西酞普兰片治疗,观察组患者在对照组基础上进行行为激活疗法。比较两组患者治疗前后汉密尔顿抑郁量表(HAMD)评分、治疗后及随访结束后服药依从性。结果两组患者治疗前HAMD评分比较,差异无统计学意义(P>0.05);观察组患者治疗后HAMD评分低于对照组(P<0.05)。两组患者治疗后HAMD评分低于治疗前(P<0.05)。观察组患者治疗后和随访结束后服药依从性均优于对照组(P<0.05)。结论采用艾司西酞普兰联合行为激活疗法治疗抑郁障碍的疗效确切,有助于改善患者的抑郁症状,同时提高患者服药依从性。
Objective To investigate the clinical effect of escitalopram combined with behavioral therapy in the treatment of depressive disorder.Methods A total of 80 cases of patients with depressive disorder were selected from September 2015 to June 2016 in Fujian Sanming Medical Association,which were randomly divided into control group（n=40） and observation group（n=40）.The control group was treated with escitalopram,and the observation group was treated with behavioral therapy based on control group.The HAMD scores before and after treatment,and medication compliance after treatment and at the end of the followed-up were compared between the two groups.Results Before treatment,no significant differences of HAMD scores was found between the two groups（P〉0.05）;after treatment,the HAMD scores of observation group were lower than control group（P〈0.05）,and the HAMD scores were lower than prior treatment（P〈0.05）.After treatment and at the end of the followed-up,the medication compliance of observation group were better than control group（P〈0.05）.Conclusion Escitalopram combined with behavioral therapy have an obviously clinical effect in treating depressive disorder,it can improve the depressive symptoms and medication compliance of patients.
出处
《临床合理用药杂志》
2017年第36期9-10,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
抑郁障碍
艾司西酞普兰
行为激活
汉密顿抑郁量表
Depressive disorder
Escitalopram
Behavioral activation
Hamilton depression scale
