摘要
目的:研究CTSA+B天然澄清剂用于神经痛口服液澄清的最佳工艺。方法:以芍药苷含量、除杂率、药液澄清情况等为考察指标,采用单因素考察法,优选最佳除杂工艺条件。结果:优选出的最佳工艺条件为:提取液浓缩至1∶7(g∶m L)的浓度;CTSA+B天然澄清剂用量,按生药计B组分为1%(g/g);B∶A=2∶1;先B后A的次序加入;搅拌速度120 r/min;在80~90℃保温;时间4 h以上。结论:CTSA+B天然澄清剂用于神经痛口服液的澄清工艺,效果良好。
Objective: To study an optimal clarification technology of Shenjingtong oral solution with clarifying agent of CTSA + B. Methods: Contents of paeoniflorin,impurity removing efficiency,and clarification of the liquid were taken as main value indexes to optimize the clarifying process with mono factor design. Results:The optimized clarifying process condition was under 1 ∶ 7 contract concentration with amount of 1% CTSB( g/g),B∶ A = 2∶ 1,with the order of B before A,keeping at 80 ~ 90℃ for 4 h and stirring under 120 r/min.Conclusion: CTSA + B can be used for the clarifying process of Shenjingtong oral solution and had good effects.
出处
《中医药信息》
2018年第2期62-65,共4页
Information on Traditional Chinese Medicine
关键词
神经痛口服液
CTSA+B
澄清工艺
Shenjingtong oral solution
CTSA + B
Clarification technology