摘要
目的分析多潘立酮不同联合用药方案治疗胆汁反流性胃炎的疗效。方法随机选择2016年1月至2017年10月在我院进行治疗的192例胆汁反流性胃炎患者进行分析,分成对照组(96例)和试验组(96例),对照组给予多潘立酮和硫糖铝药物治疗,试验组给予多潘立酮和铝碳酸镁进行治疗,对两组患者的治疗效果、胃镜征象及各项指标检测数据进行统计分析。结果试验组患者治疗总有效率(91.67%)明显高于对照组(79.17%),差异有统计学意义(P<0.05);试验组患者胃镜征象总有效率(89.58%)明显高于对照组(75.00%),差异有统计学意义(P<0.05);试验组患者的反流次数明显少于对照组,反流总时间、最长反流时间均显著短于对照组,差异均有统计学意义(P<0.05)。结论在胆汁反流性胃炎的临床治疗中,使用多潘立酮和铝碳酸镁联合药物可有效提高治疗效果,值得临床推广应用。
Objective To investigate the curative effect of different domperidone combined medication in the treatment of bile reflux gastritis. Methods One hundred and ninety-two cases of patients with bile reflux gastritis in our hospital for treatment from January 2016 to October 2017 were randomly selected and analyzed. Patients were divided into control group（96 cases） and experimental group（96 cases）. The control group was given domperidone and sucralfate drug treatment, while the experimental group was given domperidone and hydrotalcite treatment, then the therapeutic effects,gastroscopic findings and detecting data indicators of the two groups were statistically analyzed. Results The total effective rate of treatment in the experimental group（91.67%） was significantly higher than that in the control group（79.17%）, the difference was statistically significant（P〈0.05）; the total effective rate of gastroscopic signs of the experimental group was89.58%, which was significantly higher than 75.00% of the control group（P 0.05）. The number of reflux of the experimental group was significantly less than that of the control group, the total reflux time and the longest reflux time were significantly shorter than those of the control group（P 0.05）. Conclusion In the clinical treatment of bile reflux gastritis disease, domperidone combined with hydrotalcite can effectively improve the therapeutic effect, which is worthy of promotion and application in the clinical.
出处
《临床医学研究与实践》
2018年第4期21-22,共2页
Clinical Research and Practice
关键词
多潘立酮
联合用药
胆汁反流性胃炎
domperidone
combined medication
bile reflux gastritis
