摘要
目的:探讨美托洛尔联合阿托伐他汀钙对慢性心衰患者血浆hs-CRP及心功能的影响。方法:选择某院收治的慢性心力衰竭患者90例,将所有患者随机分为2组,各45例。给予对照组美托洛尔治疗,观察组在此基础上联合阿托伐他汀钙治疗,比较2组临床疗效、心功能、血浆hs-CRP水平。结果:观察组治疗后临床总有效率,LVEF,FS水平较对照组高,LVEDs,hsCRP水平较对照组低,2组比较差异具有统计学意义(P<0.05)。结论:美托洛尔联合阿托伐他汀钙可提高慢性心衰治疗效果,改善心功能,减轻炎症反应。
Objective： To investigate the effect of metoprolol combined with atorvastatin calcium on plasma hs-CRP and cardiac function in patients with chronic heart failure （CHF）. Methods ：90 CHF patients in a hospital were randomly divided into two groups, 45 cases in each. The control group was given metoprolol, while the observation group was treated with atorvastatin calcium. Clinical effi- cacy, cardiac function, and plasma hs-CRP level were compared between the two groups. Results：After the treatment, the total effective rate, LVEF, and FS levels in the observation group were higher than those in the control group, but the levels of LVEDs and hs-CRP were lower than those in the control group （ P 〈 0.05 ）. Conclusion ： Metoprolol combined with atorvastatin calcium in treatment of CHF can increase curative effect, improve cardiac function and reduce inflammatory response.
出处
《淮海医药》
CAS
2018年第2期129-131,共3页
Journal of Huaihai Medicine
