摘要
目的探讨益母草注射液联合卡前列素氨丁三醇预防高危产妇剖宫产产后出血的临床效果。方法选取2016年1月至2017年5月如皋市人民医院收治的高危妊娠产妇114例,随机分为观察组和对照组,各57例。全部剖宫产后给予静脉滴注缩宫素。对照组采用卡前列素氨丁三醇治疗,观察组在对照组基础上,给予益母草注射液治疗。记录两组产时、产后2 h、24 h出血量、恶露时间,比较两组产时及产后D-二聚体、纤维蛋白原(fibrinogen,FIB)的水平,两组不良反应发生情况。结果观察组产后2 h、24 h的出血量和恶露时间明显少于对照组,差异有统计学意义(P<0.05);两组产后3 d的D-二聚体、FIB明显降低,观察组更明显(P<0.05);观察组不良反应发生率略低于对照组,但差异无统计学意义(P>0.05)。结论益母草注射液联合卡前列素氨丁三醇能显著降低高危产妇剖宫产后的产后出血量。
Objective To investigate the effect of motherwort injection combined with prostaglandin trometamol on prevention of cesarean section postpartum hemorrhage in high - risk pregnant women. Methods 114 cases of high - risk pregnant women hospitalized in Rugao People＇s Hospital from January 2016 to May 2017 were selected and divided into observation group and control group,with 57 cases in each group. All patients were given intravenous infusion of oxytocin after cesarean section. The control group was treated with carboprost tromethamine, and the observation group was treated with motherwort injection on the basis of the control group. The amount of bleeding at 2 h and 24 h postpartum and the lochia time were recorded. The postpartum and postnatal D - dimer and fibrinogen（FIB） levels, the incidence of adverse reactions were compared between the two groups. Results The 2 h, 24 h postpartum bleeding and lochia time in the observation group were significantly lower than those of the control group. The differences were statistical significant（ P 〈 0. 05 ）. After treatment, the D - dimer and the FIB decreased significantly in two groups （ P 〈 0.05 ）.After treatment, the D - dimer and FIB in the observation group was significantly lower than that in the control group. The differences were statistical significant（P 〈 0.05 ）. The incidence of adverse reaction in the observation group was slightly lower than that of the control group, but the difference was not statistical significant （P 〉 0.05 ）. Conclusion Motherwort injection combined with prostaglandin trometamol can significantly reduce postpartum hemorrhage in high - risk parturients after cesarean section.
出处
《中国计划生育和妇产科》
2018年第3期69-72,共4页
Chinese Journal of Family Planning & Gynecotokology
关键词
益母草注射液
卡前列素氨丁三醇
高危产妇
剖宫产
产后出血
motherwort injection
prostaglandin trometamol
high risk parturient
cesarean section
postpartum hemorrhage
