摘要
目的:探讨甘精胰岛素联合复方甲亢片治疗糖尿病伴甲亢的临床疗效。结果:选取我院2016年1月至2017年3月糖尿病伴甲亢患者76例,随机分为常规组、研究组,各38例。常规组患者单纯给予甘精胰岛素进行注射,研究组在甘精胰岛素注射基础上联合复方甲亢片进行治疗,并将两组并发症发生率及空腹、餐后2 h血糖水平进行对比。另外,将两组血糖达标时间、胰岛素用量、住院时间等相关指标进行对比。结果:研究组患者并发症发生率为5.26%,显著低于常规组的23.68%;研究组患者血糖达标时间、胰岛素用量、住院天数等指标分别为(10.62±9.34)d、(43.12±10.34)U、(6.38±2.30)d,常规组为(19.73±8.67)d、(60.75±19.43)U、(9.75±4.80)d;研究组患者空腹、餐后2 h血糖水平均显著低于常规组,P<0.05。结论:相较于单一疗法,将甘精胰岛素联合复方甲亢片运用于糖尿病伴甲亢患者治疗中,可有效降低并发症发生率,减少胰岛素用量,同时缩短血糖达标时间及患者住院时间,维持血糖水平稳定性。
Objective： To investigate the clinical efficacy of insulin glargine combined with Fufangjiakang tablets in treatment of diabetes with hyperthyroidism. Methods： 76 patients with diabetes with hyperthyroidism from Ruyang county hospital of Traditional Chinese medicine in January 2016 to March 2017 were selected,and they were divided into routine group and research group by treatment regimens,38 cases in each group. Routine group was given insulin glargine injection,while research group was treated with Fufangjiakang tablets based on routine group. The incidence of complications,fasting blood glucose（FBG）,2 hour postprandial blood glucose（2 h PBG）,reaching target time of blood glucose,dosage of insulin,hospital stays were compared between the two groups. Results： The incidence of complications in research group was 5. 26%,which was lower than 23. 68% in routine group. The reaching target time of blood glucose,dosage of insulin,hospital stays in research group were（10. 62 ± 9. 34） d,（43. 12 ± 10. 34） U,（6. 38 ± 2. 30） d,and those in routine group were（19. 73 ± 8. 67） d,（60. 75 ± 19. 43） U,（9. 75 ± 4. 80） d. The levels of FBG and 2 h PBG in research group were lower than those in routine group（P〈 0. 05）. Conclusion： Compared with mono therapy,insulin glargine combined with Fufangjiakang tablets in treatment of diabetes with hyperthyroidism can decrease the incidence of complications,reduce dosage of insulin,shorten reaching target time of blood glucose and hospital stays,maintain satble blood glucose level.
出处
《中国药物评价》
2017年第6期442-444,共3页
Chinese Journal of Drug Evaluation
关键词
甘精胰岛素
复方甲亢片
糖尿病伴甲亢
疗效
Insulin Glargine
Fufangjiakang tablets
Diabetes with Hyperthyroidism
Efficacy
