摘要
目的探讨以床旁即时检测技术(POCT)检测血栓弹力图(TEG)对诊断患者凝血功能障碍的应用价值。方法收集2016年3月-2017年3月本院收治的48例以腹部创伤为主的重症创伤围术期患者为观察组,另选择同期30例健康体检者为对照组。对2组患者进行传统凝血功能检测(CCT)和TEG检测。结果观察组纤维蛋白原(FIB)、α角、MA、CI明显高于对照组,凝血酶原时间国际比值(PT-INR)、R、K明显低于对照组,上述差异均有统计学意义(P<0.05)。FIB与R、K均呈负相关,与α角、MA、CI均呈正相关(P<0.05);PT-INR与R、K、α角均呈正相关,与MA、CI均呈正相关(P<0.05)。结论应用POCT技术检测TEG,对评估重症腹部创伤患者凝血功能有一定价值,所获得的指标与CTT技术获得的FIB、PT-INT存在明显相关性,有助于判断出血风险、指导输血。
Objective To investigate the clinical value of POCT detecting TEG in the diagnosis of coagulopathy. Methods During March 2016-March 2017,48 cases of severe trauma patients（ mainly abdominal trauma） in our hospital were treated as observation group,and 30 healthy volunteers were selected in control group at the same time. Conventional coagulation function test（ CCT） and TEG test were performed in the 2 groups simultaneously. Results The fibrinogen（ FIB）,alpha angle,MA and CI in the observation group were significantly higher than those in the control group,the prothrombin time international ratio（ PT-INR）,R and K were significantly lower than those in the control group,and the differences were statistically significant（ P〈0. 05）. FIB was negatively correlated with R and K,and positively correlated with alpha angle,MA and CI（ P〈0. 05）; PT-INR was positively correlated with R,K and alpha angle,and positively correlated with MA and CI（ P〈0. 05）. Conclusion Detection of TEG using POCT technology has a certain value on the blood coagulation function in patients with severe abdominal trauma,and the acquired indexes were correlative with FIB and PT-INT obtained with CTT,which is helpful in judging the risk of bleeding,blood transfusion and guidance.
作者
吴巍
WU Wei(Clinical Laboratory, Xinhua Campus, Beijing Friendship Hospital Affiliated to Capital Medical University, Bering 101100, Chin)
出处
《中国卫生检验杂志》
CAS
2018年第5期638-640,共3页
Chinese Journal of Health Laboratory Technology
关键词
床旁即时检测技术
血栓弹力图
凝血功能
重症腹部创伤
Bedside immediate detection technique
Thrombus mapping
Coagulation function
Severe abdominal trauma
