摘要
目的初步评价添加甲基丙烯酰氧乙基-正十六烷基-二甲基氯化铵(DMAE-CB)和无定形纳米磷酸钙(NACP)的粘结剂粘结性能和抗菌性能。方法将DMAE-CB和NACP按照不同比例添加到商品化牙本质粘接剂中。按比例的不同将实验分成8组,商品化粘结剂作为对照组,用万能材料试验机进行牙本质剪切强度测试,然后进行接触性抑菌实验,研究不同分组粘结剂固化后,对变形链球菌的抗菌活性。结果对照组剪切强度为(17.96±3.45)MPa,实验组结果分别为A:(19.25±2.80)MPa,B:(18.70±2.42)MPa,C:(18.47±2.73)MPa,D:(18.22±2.50)MPa,E:(17.29±4.54)MPa,F:(18.40±2.98)MPa,G:(18.13±4.39)MPa,实验组和对照组剪切强度差异无统计学意义(P=0.993>0.05)。接触性抑菌试验的对照组无明显抗菌作用,实验组抗菌单体添加量为1%时具有明显的抗菌作用(P<0.05),当添加量为3%时,抗菌活性进一步增强,但是添加量为4%时,抗菌活性并未明显增加。结论添加了DMAE-CB和NACP的粘结剂固化后,不影响粘结强度,且具有良好的抗菌性能。
Objective To make a preliminary evaluation of the adhesive properties and antibacterial properties of methyl methacrylate bound sixteen alkyl two-ammonium chloride （DMAE-CB） and amorphous calcium phosphate （NACP） binder. Methods DMAE-CB and NACP were added to the commercial dentin adhesive according to different proportions. According to the different proportions, the experiment was divided into 8 groups, the commercialization of binder as the control group. The dentin shear strength was tested by uni- versal testing machine, and the bacteriostatic experiment was conducted, the antibacterial activity against Streptococus mutans of differ- ent groups after adhesion was studied. Results The shear strength of control group was （17.96±3.45） MPa, the experimental group were A ： （19.25±2.80） MPa, B ： （18.70±2.42） MPa, C ： （18.47±2.73） MPa, D ： （18.22±2.50） MPa, E ： （17.29±4.54） MPa, F ： （ 18.40 ±2.98） MPa, G： （18.13±4.39）MPa, through statistical analysis of P= 0.993 （P〉0.05） the shear strength of the experimental group and the control group the difference was statistically significant; the control group in the contact bacteriostatic test had antibacterial effect, the experimental group of antibacterial monomer addition 1% had significant antibacterial effects （P〈0.05）, when the dosage is 3%, the antibacterial activity was further enhanced, but when the content is 4%, the ant/bacterial activity did not significantly in- crease. Conclusion After adding DMAE-CB and NACP, the adhesive has no influence on the bond strength and has good antibacterial properties.
作者
张兆钰
孙宇
张雪
崔丹
喻望清
焦二龙
肖睿
ZHANG Zhaoyu;SUN Yu;ZHANG Xue;CUI Dan;YU Wangqing;JIAO Erlong;XIAO Rut.(Department of Prosthodontics, Stomo- tological College of Harbin Medical University, Harbin 150001, China)
出处
《口腔医学》
CAS
2018年第3期227-229,272,共4页
Stomatology
