摘要
目的:观察补肾祛瘀方对强直性脊柱炎患者临床疗效及疼痛和炎性指标的影响。方法:将60例强直性脊柱炎患者随机分为对照组和治疗组各30例,对照组给予塞来昔布片治疗(每片200 mg,上海辉瑞制药有限公司生产),每次1片,口服,每天早晚各一次。治疗组采用补肾祛瘀方治疗,药物组成:骨碎补15 g,狗脊15 g,杜仲12 g,鹿角胶15 g,延胡索15 g,续断15 g,秦艽15 g,青风藤12 g,羌活12 g。水煎服,日1次,分早晚两次温服。结果:对照组有效率为73.33%,治疗组有效率为86.67%,两组有效率比较,差异有统计学意义(P<0.05);两组患者治疗后VAS、BASDAI、BASFI积分较治疗前均明显降低,组间比较有统计学意义(P<0.05);两组患者治疗后ESR、CRP较治疗前明显降低,组间比较有统计学意义(P<0.05)。结论:补肾祛瘀方可以改善强直性脊柱炎患者临床症状和体征。
Objective： To observe the clinical curative effect of Kidney-Supplementing Stasis-Removing Decoction and the influence on pain and inflammatory indexes ofpatients with ankylosing spondylitis（AS）. Methods： Sixty patients with AS were randomly divided into the control group and the treatment group,with 30 cases in each group. The ones in the control group were treated with celecoxib tablets（200 mg per tablet,Shanghai Pfizer Pharmaceutical Co.,LTD.,）,one tablet each time,oral administration,once in the morning and evening respectively. The ones in the treatment group were treated with Kidney-Supplementing Stasis-Removing Decoction whose ingredients were as follows： Gusuibu（Rhizoma Drynariae） 15 g,Gouji（Rhizoma Cibotii） 15 g,Duzhong（Cortex Eucommiae） 12 g,Lujiaojiao（Colla Cornus Cervi） 15 g,Yanhusuo（Rhizoma Corydalis） 15 g,Xuduan（Radix Dipsaci） 15 g,Qinjiao（Radix Gentianae Macrophyllae） 15 g,Qingfengteng（Caulis Sinomenii） 12 g,Qianghuo（Rhizoma et Radix Notopterygii） 12 g,once a day for being decoction,oral administration,twice in the morning and evening respectively when it is warm. Results： The effective rate of the control group was 73. 33%,while that of the treatment group was 86. 67%.After the treatment,the two groups＇ VAS,BASDAI and BASFI scores were significantly lower than those before the treatment,and all the differences were statistically significant（P 0. 05）. Their ESR and CRP were significantly lower than those before treatment,and all the differences were statistically significant（P 0. 05）. Conclusion： Kidney-Supplementing Stasis-Removing Decoction can improve the clinical symptoms and signs of patients with ankylosing spondylitis.
作者
燕勇
YAN Yong(Zhengzhou TCM Hospital, Zhengzhou, Henan, China, 45000)
出处
《河南中医》
2018年第2期277-279,共3页
Henan Traditional Chinese Medicine
