摘要
目的了解青岛地区无偿献血人群HIV感染现状,为降低输血传播HIV风险提供依据。方法回顾性分析青岛地区2014—2016年无偿献血者HIV感染流行状况与特征。结果青岛地区2014—2016年无偿献血313 207人次,HIV初筛呈反应性180人次,反应性率为5.75/万,确认试验阳性66人次,确认试验阳性率为2.11/万。HIV确认试验阳性献血者以青年男性、初次献血、街头献血、捐献全血者居多。结论青岛地区无偿献血者HIV感染呈增高趋势,提示有必要对特定献血人群献血前进行HIV金标法快速检测。
Objective To analyze the epidemiological status and characteristics of human immunodeficiency virus（HIV） infection in voluntary blood donors from Qingdao city and proposed basic principles to reduce transfusion-transmitted HIV infection. Methods We retrospectively analyzed 313 207 blood sample records from voluntary blood donors in Qingdao city during 2014 to 2016 for HIV infection analyses. Results Blood samples from 313 207 blood donors in Qingdao from2014 to 2016 were first screened by enzyme-linked immunosorbent assay（ELISA） and nucleic acid amplification tests（NAT） to block HIV infected samples. 180 samples（5. 75/10 000） were considered reactive. Sixty-six donors among the screening positive donors were further diagnosed as infected by HIV using standardized western blot method,yielding a 2. 11/10 000 positive rate. HIV infection happened most commonly in under 40-year-old donors,first time donors,sporadic donors and whole blood donors. Conclusion Epidemic study shows a rapid increase of HIV infection rate in Qingdao voluntary blood donors since 2006,which correlated to increasing HIV infection rate in China,and supports and necessity to perform pre-donation tests with the gold strip marking method among high-risk donors.
作者
周宝琴
张霞
王同显
ZHOU Baoqin, ZHANG Xia, WANG Tongxian.(Qingdao Blood Center, Qingdao 266071, China)
出处
《中国输血杂志》
CAS
2018年第1期54-56,共3页
Chinese Journal of Blood Transfusion
关键词
无偿献血者
HIV感染
血液安全
voluntary blood donors
HIV infection
blood safety
