摘要
目的研究N末端B型钠尿肽前体(NT-pro BNP)水平变化在支气管肺炎合并心衰中的临床意义。方法回顾性分析揭阳市揭西县人民医院2015年12月-2016年12月收治的141例支气管肺炎合并心衰患儿临床资料,根据心功能评定,将患儿分为轻度心衰组、中度心衰组、重度心衰组;另选45例健康儿童作为对照组。比较治疗前后四组患儿NT-pro BNP及cTnI水平。结果治疗前,NT-pro BNP及cTnI水平比较,重度心衰组>中度心衰组>轻心衰组>对照组;治疗后,心衰组的NT-pro BNP及cTnI水平比较,轻度心衰组<中度心衰组<重度心衰组,差异有统计学意义(P<0.05)。结论 NT-pro BNP水平能够预测支气管肺炎合并心衰病情,为诊治支气管肺炎合并心衰提供可靠诊断标准,值得推广应用。
Objective To investigate the clinical significance of N terminal B type natriuretic peptide precursor（NT-pro BNP） level changes in patients with bronchopneumonia associated with heart failure.Methods A retrospective analysis of the clinical data of 141 cases of bronchopneumonia associated with heart failure in Jiexi County People＇s Hospital of Jieyang from December 2015 to December 2016 were selected. According to the assessment of cardiac function, the patients were divided into mild heart failure group, moderate heart failure group, severe heart failure group; another 45 healthy children were selected as control group. The levels of NT-pro BNP and cTnI between the four groups were compared before and after treatment. Results The NT-pro BNP and cTnI levels before treatment of severe heart failure group were successively higher than those of moderate heart failure group, mild heart failure group and control group; In the heart failure groups, the NT-pro BNP and cTnI levels after treatment of mild heart failure group were successively lower than those of moderate heart failure group and severe heart failure group. The differences were statistically significant（P〈0.05）. Conclusion The NT-pro BNP level can predict the condition of bronchopneumonia associated with heart failure, and provide reliable diagnostic criteria for the diagnosis and treatment of bronchopneumonia associated with heart failure, which is worth popularizing and applying.
作者
蔡子华
CAI Zi-hua(Department of Internal Pediatrics, Jiexi County People＇s Hospital of Jieyang, Jieyang Guangdong Province 522000, Chin)
出处
《中国城乡企业卫生》
2018年第2期88-90,共3页
Chinese Journal of Urban and Rural Enterprise Hygiene
