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大脑中动脉急性闭塞患者侧支与临床结局的CTA评价

CTA evaluation of middle cerebral artery collateral and clinical outcome in patients with acute MCA occlusion
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摘要 目的评估首次发生急性大脑中动脉(middle cerebral artery,MCA)闭塞患者的临床及影像学资料,探讨侧支循环与临床结局的相关性。方法回顾性分析确诊大脑中动脉为首发病变责任血管脑梗死的39例患者,应用CTA评估侧支循环,根据侧支循环评分,分为Pc0组、Pc1组、Pc2组,详细采集所有入组患者的一般资料,并进行NIHSS评分、脑梗死容积评分,用Logistic回归模型对各组一般资料及NIHSS评分、脑梗死容积数据进行分析。各侧支循环级别组间高危因素比较差异无统计学意义。结果 Pc0组患者NIHSS评分、脑梗死容积评分高于Pc1组及Pc2组。结论病变责任血管为大脑中动脉的急性期脑梗死患者,利用CTA影像可有效评估侧支循环的建立状态,对脑梗死的临床诊断和治疗方案的选择具有重要的指导价值,同时对临床结局的预测提供有力依据。 Objective To study the relationship between collateral circulation and clinical outcome by assessing the clinical manifestation and image data in patients with the first occlusion of MCA(middle cerebral artery). Methods 39 patients with the first occlusion of MCA were retrospectively analyzed and divided into three groups(Pc0,Pc1,Pc2) according to the collateral circulation score, which were scored by the CTA. All these patients were collected general clinical data, and scored by NIHSS, and their infarction volume. Correlations among general data,NIHSS score and cerebral infarction volume in the patients were analyzed by Logistic regression mode. Results The high-risk factors of each group had no significant differences. The scores of NIHSS and cerebral infarction volume of Pc0 were higher than Pcl and Pc2. Conclusion CTA can iudge and predict the degree of cerebral infarction. It has important value in the guidance for clinical treatment and the selection of treatment. At the same time CTA can provide powerful basis for the forecast of clinical outcomes.
作者 孙九艳 李菁 李娜 杨清成 SUN Jiuyan1,LI Jing2,LI Na3,YANG Qingcheng1(1.Department of Neurology, People's Hospital of Anyang,Anyang 455000, China; 2.Department of Neurology, the First People's Hospital of Zhengzhou Unlversity ,Zhengzhou 450052, China;3. Department of Imaging, People's Hospital of Anyang , Anyang 455000, Chin)
出处 《中国实用神经疾病杂志》 2018年第5期526-530,共5页 Chinese Journal of Practical Nervous Diseases
基金 安阳市科技局项目(20080012)
关键词 大脑中动脉 脑梗死 侧支循环 CTA 临床结局 Middle cerebral artery Cerebral infarction Collateral circulation CTA Clinical outcome
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