摘要
目的对比分析踝肱和趾肱指数在预测2型糖尿病微血管并发症与大血管并发症发生风险中的价值。方法收集比较受试对象既往踝肱和趾肱指数水平及相关影响因素并进行讨论和分析,应用SPSS 20.0统计软件分析。结果不同性别、不同血糖控制水平患者间ABI与TBI分布特征的比较提示,无论男女均可见单纯糖尿病组患者ABI和TBI异常比例最低。血糖控制优良的患者中,三组患者ABI和TBI异常的比例均显示微血管病变和大血管病变患者比例高于单纯糖尿病组患者,P<0.05;在血糖控制不佳的患者中也见到类似趋势;三组患者血糖控制不佳者ABI和TBI异常的比例均分别高于血糖控制良好者,P<0.05;回归分析提示ABI和TBI异常均为三种并发状态发生的危险因素,均有P<0.05;调整了性别年龄、血糖控制水平后仍均表现为危险因素,P<0.05。结论 ABI与TBI的异常可以作为预测2型糖尿病患者微血管以及大血管病变的预测因子在临床中起到重要作用。
Objective To compare the value of ankle brachial and toe brachial index in predicting the risk of microvascular complications and major vascular complications in type 2 diabetes mellitus. Methods The levels of ankle brachial and brachial index and related influencing factors were compared and analyzed by SPSS 20.0 statistical software. Results The comparison of the distribution characteristics of ABI and TBI among different sex and different blood glucose control levels showed that the ratio of ABI and TBI was the lowest among both men and women in diabetic alone group. In patients with excellent blood glucose control, the proportion of ABI and TBI abnormalities in both groups showed a higher proportion of patients with microvascular disease and macrovascular disease than in diabetic patients alone （ P 〈 0.05 ）. Similar trends were seen in patients with poor blood glucose control （ P 〈 0.05 ）. The regression analysis showed that ABI and TBI abnormalities were the risk factors of three concurrent states, and all of them had the risk factors of AB1 and TBI abnormality, P 〈 0.05. After adjusted with gender and age, and blood glucose control level, they still showed as risk factors, P 〈 0.05. Conclusion Abnormal ABI and TBI can play an important clinical role in predicting microvessels and macrovascular disease in type 2 diabetic patients.
作者
李婷婷
LI Ting- ting(Department of Endocrinology, Beijing Fengtai Hospital, Beijing 100071, Chin)
出处
《标记免疫分析与临床》
CAS
2018年第3期345-348,共4页
Labeled Immunoassays and Clinical Medicine
关键词
踝肱指数
趾肱指数
2型糖尿病
微血管并发症
大血管并发症发生
预测
Ankle- brachial index
Toe brachial index
Type 2 diabetes mellitus
Microvascular complications
Macrovascular complications
