摘要
目的探讨老年急性冠脉综合征(ACS)病人经皮冠状动脉介入治疗(PCI)术后慢血流事件的危险因素。方法回顾性分析行PCI治疗的ACS病人95例,包括不稳定型心绞痛(UAP)59例和急性心肌梗死(AMI)36例,依据其是否发生慢血流事件分为慢血流组(n=32)和血流正常组(n=63)。比较2组的一般临床资料及尿素氮(BUN)、肌酐(SCr)和D-二聚体(D-dimer)等指标水平,采用多因素Logistic回归分析慢血流发生的危险因素。结果 2组的年龄、糖尿病史、高血脂、吸烟史及D-dimer水平比较,差异均有统计学意义(P<0.05);Logistic回归分析表明,年龄(OR=3.618,95%CI:1.337~7.522)、糖尿病史(OR=4.781,95%CI:1.405~7.724)、高血脂(OR=5.026,95%CI:1.520~9.875)、吸烟史(OR=5.155,95%CI:1.596~10.337)和D-dimer(OR=5.547,95%CI:1.662~11.347)与PCI术后慢血流事件的发生独立相关。结论年龄、糖尿病史、高血脂、吸烟史和D-dimer是PCI术后慢血流事件发生的危险因素。
Objective To investigate the risk factors of slow flow events after percutaneous coronary intervention( PCI) in elderly patients with acute coronary syndrome( ACS).Methods A retrospective analysis was performed in 95 patients with ACS treated with PCI,including 59 cases of unstable angina pectoris( UAP) and 36 cases of acute myocardial infarction( AMI).According to the occurrence of slow flow events,the patients were divided into slow blood flow group( n = 32) and normal blood flow group( n =63).The clinical data and the levels of blood ureg nitrogen( BUN),serum creatinine( SCr) and D-dimer were compared between two groups,and the risk factors of slow blood flow were analyzed by Logistic regression.Results There were significant differences in age,history of diabetes,hyperlipidemia,smoking history and level of D-dimer between two groups( P〈0.05),Logistic regression analysis showed that age( OR = 3.618,95% CI: 1.337-7.522),history of diabetes( OR = 4.781,95% CI: 1.405-7.724)hyperlipidemia,( OR = 5.026,95% CI: 1.520-9.875),smoking history( OR = 5.155,95% CI: 1.596-10.337),and D-dimer( OR = 5.547,95% CI: 1.662-11.347) were independently associated with the occurrence of slow flow events( P〈0.05).Conclusions Age,diabetes history,hyperlipidemia,smoking history and D-dimer are the risk factors for the occurrence of slow flow events after PCI.
作者
陈雪梅
何艳萍
余勰
张贵方
CHEN Xue-mei, HE Yan-ping, YU Xie, ZHANG Gui-fang.(Emergency ICU, Chongqing Traditional Chinese Medicine Hospital, Chongqing 400021, Chin)
出处
《实用老年医学》
CAS
2018年第3期249-251,共3页
Practical Geriatrics