摘要
目的:通过分析在我院住院,头颅MRI检查符合胆红素脑病诊断的新生儿,结合其临床表现,了解新生儿头颅MRI结果异常与临床表现间的关系。方法:收集2016年1月～2017年6月在我院住院,诊断为新生儿高胆红素血症且行头颅MRI检查提示符合胆红素脑病的患儿,通过对其临床表现和辅助检查结果进行分析,了解头颅MRI结果异常与临床表现和预后的关系。结果:在33例头颅MRI检查符合胆红素脑病的患儿中,有31例表现为苍白球区T1WI高信号,10例表现为丘脑区T1WI高信号,3例表现为脑干T1WI高信号,3例分别表现为小脑蚓部T1WI异常高信号,小脑齿状核对称性短T1信号。在33例患儿中,仅有6例出现胆红素脑病的症状,影像学及临床表现均符合胆红素脑病的诊断。结论:头颅MRI是目前诊断胆红素脑病的客观依据之一,在没有神经系统异常症状的新生儿中,胆红素脑病的诊断需慎重,避免过度诊断和治疗。
Objective： By analyzing newborns who were admitted to our hospital and diagnosed of bilirubin encephalopathy by MRI examination, the objective of this research was to understand the relationship between abnormal head MRI results of newborn and clinical manifestations. Methods：Newborn patients who were admitted to our hospital and diagnosed of hyperbilirubinemia and whose head MRI examination revealed bilirubin encephalopathy from January 2016 to June 2017 were collected. The correlation of abnormal head MRI results with clinical manifestations and prognosis wax explored by analyzing their clinical manifestations and auxiliary examination results. Results： Among 33 patients whose head MRI results revealed bilirubin encephalopathy, 31 were characterized by T1WI high signal in the pallidum, 10 were characterized by T1WI high signal in the thalamus, 3 were characterized by T1WI high signal in the brainstem, and 3 were characterized by T1WI abnormally high signal in vermis cerebelli and symmetrical short T1 signal in cerebellar dentate nuclei respectively. Of these 33 newborn patients, only 6 had the symptoms of bilirubin encephalopathy, and their imaging and clinical manifestations suggested bilirubin encephalopathy. Conclusion： Head MRI is currently one of the objective evidences for the diagnosis of bilirubin encephalopathy. For newborns with no symptoms of neurologic abnormality, the diagnosis of bilirubin encephalopathy should be prudent to avoid over-diagnosis and over-treatment.
作者
杨乔焕
陈小岸
YANG Qiao-huan CHEN Xiao-an(Guangdong NO.2 Provincial People＇s hospital, Guangdong Guangzhou 51000)
出处
《按摩与康复医学》
2018年第8期68-70,共3页
Chinese Manipulation and Rehabilitation Medicine
关键词
高胆红素血症
苍白球
胆红素脑病
磁共振成像
Hyper-bilirubinemia
Globus pallidus
Bilirubin Encephalopathy
Magnetic resonance imaging
