摘要
目的观察雪莲注射液联合关节镜手术治疗老年膝骨关节炎的临床疗效。方法对我院108例老年膝关节炎患者采用雪莲注射液或玻璃酸钠注射液联合关节镜手术治疗的临床资料进行回顾性分析。根据注射物的不同,分为雪莲组和对照组。其中,雪莲组关节镜术后1、2、3、4、5周,每周关节腔内注射雪莲注射液2mL。对照组关节腔内注射玻璃酸钠注射液2mL。两组患者均出院后于术后5周、3个月、6个月、12个月骨科门诊复查,并进行随访,根据Lysholm膝关节评分系统进行评分。结果 108例患者均获得随访,随访12～24个月,平均18.2个月,未出现手术切口感染病例。根据Lysholm评分标准,雪莲组术后6个月评分为(89.8±6.9)、12个月为(88.3±7.6);对照组术后6个月评分为(84.6±4.7)、12个月为(83.2±4.8);雪莲组优良率术后6个月为75.5%,术后12个月为71.7%,对照组优良率术后6个月为67.3%,术后12个月为61.8%,两组间对比有显著性差异(均P<0.05)。结论对于老年膝骨关节炎患者,采用雪莲注射液联合关节镜手术治疗,取得了良好的临床疗效,是一种可靠的治疗选择。
Objective To observe the clinical effect of Xuelian injection combined with arthroscopic surgery in treatment of knee osteoarthritis （KOA） in the elderly. Methods 108 cases of elderly patients with KOA received Xuelian injection or sodium hyaluronate injection combined with arthroscopic treatment were retrospectively analyzed. According to the different injections, the patients were divided into treatment group and control group.Treatment group received intraoperative injection of Xuelian injection 2mL, control group received intraperitoneal injection of sodium hyaluronate injection 2mL at the 1st, 2nd, 3rd,4th,5th weeks after arthroscopy. Both groups received orthopaedic outpatient care at the 5th weeks, the 3rd, 6th 12th months after discharge, and followed up and scored according to Lysholm knee score system. Results 108 patients were followed up for 12 to 24 months, an average of 18.2 months, no surgical incision infection cases. According to the Lysholm score, the score was （89.8±6.9） at the 6th month and （88.3±7.6） at the 12th month in treatment group. Control group had a score of （84.6±4.7） at the 6th month and （83.2±4.8） at the 12th month; the excellent and good rate of treatment group was 75.5% at the 6th month and 71.7% at the 12th month after operation; the excellent rate of control group was 67.3% at the 6th month and 61.8% at the 12th month after operation, the differences were significant （P〈0.05）. Conclusion Xuelian injection combined with arthroscopic can achieve good clinical efficacy in elderly patients with KOA, it is a reliable treatment option.
作者
杨傲飞
邹季
任婕
何承建
张志文
YANG Aofei;ZOU Ji;REN Jie;HE Chengjian;ZHANG Zhiwen(Hubei University of Chinese Medicine, Wuhan 430061;Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan 430061)
出处
《湖北中医药大学学报》
2018年第2期84-87,共4页
Journal of Hubei University of Chinese Medicine
基金
卫生部医药卫生科技发展研究中心(项目编号:W2013ZT120)
湖北省中医院青年项目课题(项目编号:2014Z58)
关键词
骨关节炎
雪莲注射液
关节镜
功能锻炼
osteoarthritis
Xuelian injection
arthroscopy
functional exercise
