摘要
选取中华圆田螺为受试动物,探究氟对其肝胰脏抗氧化酶SOD、GSH、POD活性和丙二醛(MDA)含量的影响。结果显示,在不同浓度水氟环境条件下(0、40、80、160 mg·L^(-1))连续暴露10 d、20 d和30 d时,与对照组相比,中华圆田螺肝胰脏SOD活性在暴露前20 d,中低浓度组活性被诱导升高,高浓度组受抑制降低。暴露30 d时,中低浓度组活性降低,高浓度组逐渐升高。MDA含量在暴露前20 d时,中低浓度组活性整体被诱导升高,高浓度组受抑制降低。暴露30 d时,MDA含量受到显著抑制均低于对照组。GSH活性以诱导为主均高于对照组,POD活性在10 d时均低于对照组,而在20 d时被诱导升高且均高于对照组,30 d时中高浓度以抑制为主。上述研究结果为水质污染控制及生态风险评价提供了基础数据。
The effects of fluoride on the activities of antioxidant enzymes（SOD, GSH and POD） and MDA levels were measured in hepatopancreas of Cipangopaludina cahayensis exposed to different concentrations of fluoride（0,40, 80, 160 mg·L^（-1）） for 30 days. The results indicated that compared with the control group, SOD activities were induced in the low concentration group but were inhibited in the high concentration group after 20 days exposure.After exposure for 30 days, SOD activities were decreased in hepatopancreas of Cipangopaludina cahayensis exposed to low and medium concentration fluoride, while were gradually increased in high concentration group.MDA contents were induced in the hepatopancreas of Cipangopaludina cahayensis exposed to low and medium concentrations while were inhibited in the high concentration group for 20 days. After exposure for 30 days, theMDA contents were significantly inhibited compared with that in the control group. GSH activities were higher in the hepatopancreas of Cipangopaludina cahayensis during the whole exposure period. POD activities were decreased compared with those in the control group after 10 days exposure, and then were elevated after 20 days exposure, while were inhibited after 30 days exposure. All the results would provide the basic data for water pollution control and ecological risk assessment.
作者
陈剑杰
曹谨玲
李潇
阴晴朗
Chen Jianjie;Cao Jinling;Li Xiao;Yin Qinglang(College of Animal Science and Veterinary Medicine, Shanxi Agricultural University/Key Laboratory of Ecological Animal Husbandry and Environmental Veterinary Medicine of Shanxi Province, Taigu 030801, China)
出处
《生态毒理学报》
CAS
CSCD
北大核心
2018年第1期268-273,共6页
Asian Journal of Ecotoxicology
基金
国家自然科学基金(31440087
31502141)
中国博士后科学基金项目(2012M520601
2013T60267)
山西农业大学科研启动基金(XB2007003)
山西农业大学博士后基金(92462)
山西农业大学科技创新基金(2009005)
关键词
氟
中华圆田螺
抗氧化酶
丙二醛
fluoride
Cipangopaludina cahayensis
hepatopancreas
antioxidant related enzymes
MDA
