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A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension 被引量:5

A meta-analysis of soluble suppression of tumorigenicity 2 (sST2) and clinical outcomes in pulmonary hypertension
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摘要 Suppression of Tumorigenicity 2 (ST2) is a member of the interleukin (IL)-1 receptor family The ST2 receptor exists in two isoforms - ST2 ligand (ST2L) and soluble ST2 (sST2).ST2L is a membrane receptor and sST2 is a trun- cated receptor which is soluble in the blood, allowing it to be detected in serum. IL-33 is a member of the IL-1 family of ligand and is the fimctional ligand of ST2L receptor. It binds to the ST2L, thereby mediating its immune function.
出处 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2017年第12期766-771,共6页 老年心脏病学杂志(英文版)
关键词 MORTALITY Poor outcomes Pulmonary hypertension Soluble suppression of tumorigenicity 2 SST2 高血压 临床 膜受体 ST2 IL-1 免疫力 家庭
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