摘要
目的比较保乳手术与根治性手术治疗早期乳腺癌的临床效果及并发症发生情况。方法回顾性分析我院近两年收治的80例乳腺癌患者的临床资料,按照手术方法分为观察组(保乳手术)与参考组(根治性手术),每组40例。观察两组手术情况、住院时间、临床治疗效果、术后并发症发生情况、癌症患者生命质量测定的核心模块(QLQ-C30)评分与乳腺癌特异模块(QLQ-BR23)评分;记录两组患者术后3年内复发情况及患者生存率。结果观察组手术时间、切口长度、术中出血量及术后住院时间均明显短于参考组(P<0.05);观察组美容效果明显优于参考组(P<0.05),观察组术后并发症发生率与参考组比较存在明显差异性(P<0.05);治疗前,两组QLQ-C30、QLQ-BR23评分差异无统计学意义(P>0.05),治疗后两组QLQ-C30、QLQ-BR23评分出现明显改善且观察组改善程度明显优于参考组(P<0.05);观察组术后3年内复发率、患者生存率与参考组差异无统计学意义(P>0.05)。结论保乳手术与根治性手术治疗早期乳腺癌的效果均比较理想,可以达到满意治疗效果,保乳手术安全性更高,且更加美观,可作为首选手术方式推广使用。
Objective To compare the clinical effects and complications of breast-conserving surgery and radical surgery in the treatment of early-stage breast cancer. Methods The clinical data of 80 cases of breast cancer patients who were admitted to our hospital in the past two years were retrospectively analyzed. According to the surgical methods, the patients were divided into the observation group（breast conserving surgery） and the reference group（radical surgery）, with 40 cases in each group. The surgical condition, length of stay, clinical curative effect, incidence of post operative complications, the score of core module for evaluating life quality（QLQ-C30） and the score of breast cancer specific module（QLQ-BR23） of the cancer patients were observed in both groups; the recurrence and survival rate of patients in the two groups within 3 years after surgery were recorded. Results The surgery time, incision length, intraoperative blood loss and postoperative length of hospital stay in the observation group were significantly shorter than those in the reference group（P〈0.05）; the aestheti effect in the observation group was significantly better than that in the reference group（P〈0.05）. The incidence rate of postoperative complications in the observation group was significantly different from that in the reference group（P〈0.05）; before treatment, QLQ-C30 and QLQ-BR23 scores of the two groups were not statistically significant（P〉0.05）. After treatment, the QLQ-C30 and QLQ-BR23 scores of two groups were improved significantly and the improvement degree in the observation group was significantly better than that in the refer ence group（P〈0.05）; the recurrence rate within 3 years after operation and the patients＇ survival rate in the observation group were not statistically different from those in the reference group（P〉0.05）. Conclusion The effect of breast-conserving surgery and radical surgery in the treatment of early breast cancer are ideal, which can achieve satisfactory therapeutic effect. Breast-conserving surgery has a higher safety and the aesthetic effect is favorable, which can be used as the first surgical approach for promotion and application.
作者
崔斌斌
吴增贵
王玉玲
CUI Binbin;WU Zenggui;WANG Yuling(Department of Breast and Thyroid Surgery, Taizhou Hospital in Zhejiang Province, Linhai 317000, China)
出处
《中国现代医生》
2018年第9期42-45,共4页
China Modern Doctor
基金
浙江省自然科学基金(LY15H160002)
关键词
保乳手术
根治性手术
早期乳腺癌
生命质量
美学效果
Breast-conserving surgery
Radical surgery
Early-stage breast cancer
Quality of life
Aesthetic effect
